Adipose is a key tissue regulating energy homeostasis. In states of obesity, caloric intake
exceeds energy expenditure, thereby accelerating lipid accumulation with ongoing …

Insulin resistance (IR) refers to a reduction in the ability of insulin to exert its metabolic
effects in organs such as adipose tissue (AT) and skeletal muscle (SM), leading to chronic …

Background & Aims Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic
steatohepatitis (NASH) are emerging as leading causes of liver disease worldwide …

Diabetic kidney disease (DKD) is the most common cause of severe renal disease
worldwide and the single strongest predictor of mortality in diabetes patients. Kidney …

Adipose tissue macrophages (ATMs) regulate the occurrence of obesity and its related
diseases. Here, we found that serine/threonine protein kinase 24 (Stk24) expression is …

Since the discovery of the mammalian sterile twenty (MST) kinase family of proteins
(MST1/STK4, MST2/STK3, MST3/STK24, and SOK1/STK25), much has been done that adds …

In the heart, protein kinase A (PKA) is critical for activating calcium handling and sarcomeric
proteins in response to beta-adrenergic stimulation leading to increased myocardial …

Serine/threonine protein kinase 25 (STK25) has critical importance for diabetic
complications. However, whether STK25 has a link with diabetic retinopathy is not clearly …

Nonalcoholic fatty liver disease (NAFLD) is defined by excessive accumulation of lipid
droplets within hepatocytes. The STE20‐type kinases comprising the germinal center kinase …

Ectopic lipid storage in the liver is considered the main risk factor for nonalcoholic
steatohepatitis (NASH). Understanding the molecular networks controlling hepatocellular …