Pain is an unpleasant sensation associated with a wide range of injuries and diseases, and
affects approximately 20% of adults in the world. The discovery of new and more effective …

Ethnopharmacological relevance Ophiorrhiza rugosa var. prostrata is a traditional medicinal
plant used by the indigenous and local tribes (Chakma, Marma and Tanchangya) of …

Oxidative stress-related cartilage degeneration, synovitis, and joint pain play vital roles in
the progress of osteoarthritis (OA). Anti-oxidative stress agents not only prevent structural …

Benfotiamine has shown therapeutic efficacy in the treatment of painful diabetic neuropathy
in human beings. However, so far there is no evidence about the efficacy of this drug in …

Abstract Ethnopharmacological relevance Holigarna caustica (Dennst.) is commonly used in
traditional medicine to treat a variety of painful conditions such as eye irritation …

The present study was conducted to evaluate the analgesic effects of po, ip, or icv
administration of ellagic acid (EA), and investigate the possible mechanisms underlying the …

The objectives of the present study were to determine the mechanisms of antinociceptive
effect of methanol extract of Clinacanthus nutans (Acanthaceae) leaves (MECN) using …

Muntingia calabura L.(family Elaeocarpaceae) has been traditionally used to relieve various
pain‐related ailments. The present study aimed to determine the antinociceptive activity of …

This study investigated the antinociceptive effects of zerumbone in chemical behavioural
models of nociception in mice. Zerumbone given through intraperitoneal route (ip) produced …

The fresh rhizome of Zingiber zerumbet Smith (Zingiberaceae) is used as a food flavoring
and also serves as a folk medicine as an antipyretic and for analgesics in Taiwan …