The brain of Drosophila melanogaster is comprised of some 100,000 neurons, 127 and 80
of which are dopaminergic and serotonergic, respectively. Their activity regulates behavioral …

Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …

The fruit fly can evaluate its energy state and decide whether to pursue food-related cues.
Here, we reveal that the mushroom body (MB) integrates hunger and satiety signals to …

Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …

Although painful stimuli elicit defensive responses including escape behavior for survival,
starved animals often prioritize feeding over escape even in a noxious environment. This …

Rapid and efficient escape behaviors in response to noxious sensory stimuli are essential
for protection and survival. Yet, how noxious stimuli are transformed to coordinated escape …

How glia control axon regeneration remains incompletely understood. Here, we investigate
glial regulation of regenerative ability differences of closely related Drosophila larval …

Modulation of nociception allows animals to optimize chances of survival by adapting their
behaviour in different contexts. In mammals, this is executed by neurons from the brain and …

The mechanisms by which synaptic partners recognize each other and establish appropriate
numbers of connections during embryonic development to form functional neural circuits are …

At the cellular level, α-tubulin acetylation alters the structure of microtubules to render them
mechanically resistant to compressive forces. How this biochemical property of microtubule …