Revisiting biomarker discovery by plasma proteomics

PE Geyer, LM Holdt, D Teupser… - Molecular systems biology, 2017 - embopress.org
Clinical analysis of blood is the most widespread diagnostic procedure in medicine, and
blood biomarkers are used to categorize patients and to support treatment decisions …

Biomolecular and bioanalytical applications of infrared spectroscopy–A review

KB Beć, J Grabska, CW Huck - Analytica chimica acta, 2020 - Elsevier
Infrared (IR; or mid-infrared, MIR; 4000-400 cm− 1; 2500–25,000 nm) spectroscopy has
become one of the most powerful and versatile tools at the disposal of modern bioscience …

Gas chromatography-mass spectrometry (GC-MS)-based metabolomics

A Garcia, C Barbas - Metabolic profiling: Methods and protocols, 2011 - Springer
Metabolic fingerprinting, the main tool in metabolomics, is a non-targeted methodology
where all detectable peaks (or signals), including those from unknown analytes, are …

Impact of blood collection devices on clinical chemistry assays

RAR Bowen, GL Hortin, G Csako, OH Otañez… - Clinical …, 2010 - Elsevier
Blood collection devices interact with blood to alter blood composition, serum, or plasma
fractions and in some cases adversely affect laboratory tests. Vascular access devices may …

Serum and plasma proteomics

HJ Issaq, Z Xiao, TD Veenstra - Chemical reviews, 2007 - ACS Publications
There is a saying,“Eyes are the windows to the soul”. In much the same vein, blood, since it
flows through the entire body, can be considered the window to the physical condition of the …

Recent advances in SPME techniques in biomedical analysis

H Kataoka, K Saito - Journal of pharmaceutical and biomedical analysis, 2011 - Elsevier
Biomedical analyses of drugs, metabolites, poisons, environmental and occupational
pollutants, disease biomarkers and endogenous substances in body fluids and tissues are …

The known unknowns: an overview of the state of blood-based protein biomarkers of mild traumatic brain injury

SJ McDonald, SR Shultz, DV Agoston - Journal of Neurotrauma, 2021 - liebertpub.com
Blood-based protein biomarkers have revolutionized several fields of medicine by enabling
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …

Capillary electrophoresis‐mass spectrometry for intact protein analysis: Pharmaceutical and biomedical applications (2018–March 2023)

K Maráková, M Opetová… - Journal of Separation …, 2023 - Wiley Online Library
Capillary electrophoresis is recognized as a valued separation technique for its high
separation efficiency, low sample consumption, good economic and ecological aspects …

Screening techniques for the identification of bioactive compounds in natural products

Y Fu, J Luo, J Qin, M Yang - Journal of pharmaceutical and biomedical …, 2019 - Elsevier
Natural products (NPs) have a long history of clinical use and are rich source of bioactive
compounds. The development of tools and techniques for identifying and analyzing NP …

[HTML][HTML] Matrix-assisted laser desorption ionization time-of-flight mass spectrometry identifies 90% of bacteria directly from blood culture vials

W Moussaoui, B Jaulhac, AM Hoffmann… - Clinical microbiology …, 2010 - Elsevier
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)
is now widely used for marker/multibiomarker detection in medical diagnosis. We tested a …