Antimicrobial activity of 1, 3, 4-oxadiazole derivatives
The worldwide development of antimicrobial resistance forces scientists to search for new
compounds to which microbes would be sensitive. Many new structures contain the 1, 3, 4 …
compounds to which microbes would be sensitive. Many new structures contain the 1, 3, 4 …
Carbazole derivatives as potential antimicrobial agents
Microbial infection is a leading cause of death worldwide, resulting in around 1.2 million
deaths annually. Due to this, medicinal chemists are continuously searching for new or …
deaths annually. Due to this, medicinal chemists are continuously searching for new or …
π–π noncovalent interaction involving 1, 2, 4-and 1, 3, 4-oxadiazole systems: The combined experimental, theoretical, and database study
A series of N-pyridyl ureas bearing 1, 2, 4-(1a, 2a, and 3a) and 1, 3, 4-oxadiazole moiety
(1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as …
(1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as …
Synthesis, characterization, cytotoxicity analysis and evaluation of novel heterocyclic derivatives of benzamidine against periodontal disease triggering bacteria
Periodontal disease (PD) is multifactorial oral disease that damages tooth-supporting tissue.
PD treatment includes proper oral hygiene, deep cleaning, antibiotics therapy, and surgery …
PD treatment includes proper oral hygiene, deep cleaning, antibiotics therapy, and surgery …
Synthesis, characterization, and biologic activity of new acyl hydrazides and 1, 3, 4-oxadiazole derivatives
Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides and 1, 3,
4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic acids were synthesized and …
4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic acids were synthesized and …
Biological evaluation and molecular docking studies of novel 1, 3, 4-oxadiazole derivatives of 4, 6-dimethyl-2-sulfanylpyridine-3-carboxamide
To date, chronic inflammation is involved in most main human pathologies such as cancer,
and autoimmune, cardiovascular or neurodegenerative disorders. Studies suggest that …
and autoimmune, cardiovascular or neurodegenerative disorders. Studies suggest that …
Antiproliferative copper (II) complexes bearing mixed chelating ligands: structural characterization, ROS scavenging, in silico studies, and anti-melanoma activity
Melanoma is a skin cancer characterized by rapid growth and spread for which current
therapies produce both resistance and increased risk of infection. To develop new anti …
therapies produce both resistance and increased risk of infection. To develop new anti …
In silico and experimental investigation of the biological potential of some recently developed carprofen derivatives
The efficient regioselective bromination and iodination of the nonsteroidal anti-inflammatory
drug (NSAID) carprofen were achieved by using bromine and iodine monochloride in glacial …
drug (NSAID) carprofen were achieved by using bromine and iodine monochloride in glacial …