Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible
structural and functional changes in the joint and is a major cause of disability and reduced …

The prevalence of osteoarthritis (OA) and the burden associated with the disease are
steadily increasing worldwide, representing a major public health challenge for the coming …

More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

Osteoarthritis (OA) can be regarded as a chronic, painful and degenerative disease that
affects all tissues of a joint and one of the major endpoints being loss of articular cartilage. In …

Introduction Osteoarthritis (OA) is an inflammatory disease of the joints that causes
progressive disability in the elderly. Reactive oxygen species (ROS) play an important role …

Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be
observed both at the cartilage surface and in its deeper layers. The formation of calcium …

Objective To assess the efficacy and safety of the anti–interleukin‐1α/β (anti–IL‐1α/β) dual
variable domain immunoglobulin lutikizumab (ABT‐981) in patients with knee osteoarthritis …

Recent studies have revealed novel forms of cell death beyond the canonical types of
cellular apoptosis and necrosis, and these novel forms of cell death are induced by extreme …

Abstract Purpose of Review The purpose of this review is to update the reader on the current
applications of platelet-rich plasma (PRP) in the treatment of knee osteoarthritis (KOA). This …

Inflammatory changes are observed in affected joints of osteoarthritis (OA) patients and are
thought to be involved in the pathology that develops along OA progression. This narrative …