Recent advances in archaeal translation initiation

E Schmitt, PD Coureux, R Kazan, G Bourgeois… - Frontiers in …, 2020 - frontiersin.org
Translation initiation (TI) allows accurate selection of the initiation codon on a messenger
RNA (mRNA) and defines the reading frame. In all domains of life, translation initiation …

Insights into the Vibrio Genus: A One Health Perspective from Host Adaptability and Antibiotic Resistance to In Silico Identification of Drug Targets

PH Marques, LCS Prado, AG Felice, TCV Rodrigues… - Antibiotics, 2022 - mdpi.com
The genus Vibrio comprises an important group of ubiquitous bacteria of marine systems
with a high infectious capacity for humans and fish, which can lead to death or cause …

A rationally designed antimicrobial peptide from structural and functional insights of Clostridioides difficile translation initiation factor 1

E Alanis, F Aguilar, N Banaei, FB Dean… - Microbiology …, 2024 - Am Soc Microbiol
ABSTRACT A significant increase of hospital-acquired bacterial infections during the COVID-
19 pandemic has become an urgent medical problem. Clostridioides difficile is an urgent …

Targeting and function of proteins mediating translation initiation in organelles of Plasmodium falciparum

A Haider, SM Allen, KE Jackson… - Molecular …, 2015 - Wiley Online Library
The malaria parasite P lasmodium falciparum has two translationally active organelles–the
apicoplast and mitochondrion, which import nuclear‐encoded translation factors to mediate …

Structure-Guided Computational Approaches to Unravel Druggable Proteomic Landscape of Mycobacterium leprae

SC Vedithi, S Malhotra… - Frontiers in Molecular …, 2021 - frontiersin.org
Leprosy, caused by Mycobacterium leprae (M. leprae), is treated with a multidrug regimen
comprising Dapsone, Rifampicin, and Clofazimine. These drugs exhibit bacteriostatic …

Solution structure of protein synthesis initiation factor 1 from Pseudomonas aeruginosa

Y Hu, A Bernal, JM Bullard, Y Zhang - Protein Science, 2016 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic bacterial pathogen and a primary cause of
nosocomial infection in humans. The rate of antibiotic resistance in P. aeruginosa is …

A Rationally Designed Antimicrobial Peptide from Structural and Functional Insight of Clostridium difficile Translation Initiation Factor 1

E Alanis, F Aguilar, N Banaei, FB Dean, M Alanis… - bioRxiv, 2023 - biorxiv.org
A significant increase of hospital-acquired bacterial infections during the COVID-19
pandemic has become an urgent medical problem. Clostridioides difficile is an urgent …

Structure and dynamics study of translation initiation factor 1 from Staphylococcus aureus suggests its RNA binding mode

DH Kim, SJ Kang, KY Lee, SB Jang, SM Kang… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Translation initiation, the rate-limiting step in the protein synthesis, is tightly regulated. As
one of the translation initiation factors, translation initiation factor 1 (IF1) plays crucial roles …

Structural and Functional Insight of Helicobacter pylori Translation Initiation Factor IF1 (HpIF1) in Protein Biosynthesis and Rational Design of New Antimicrobial …

A Shahriar - 2023 - search.proquest.com
Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the human gastric
mucosa and is associated with peptic ulcer disease and gastric cancer. Bacterial protein …

[PDF][PDF] Insights into the Vibrio Genus: A One Health Perspective from Host Adaptability and Antibiotic Resistance to In Silico Identification of Drug Targets. Antibiotics …

PH Marques, L da Silva Prado, AG Felice… - 2022 - researchgate.net
The genus Vibrio comprises an important group of ubiquitous bacteria of marine systems
with a high infectious capacity for humans and fish, which can lead to death or cause …