Effect of pharmaceutical excipients on micellization of Pluronic and the application as drug carrier to reverse MDR
Y Li, Y Tian, X Jia, Z Zhang, D Sun, H Xie… - Journal of Molecular …, 2023 - Elsevier
Linear amphiphilic triblock copolymers Pluronic, poly (ethylene oxide)-poly (propylene
oxide)-poly (ethylene oxide)(PEO-PPO-PEO) have been widely used in controllable drug …
oxide)-poly (ethylene oxide)(PEO-PPO-PEO) have been widely used in controllable drug …
Self-assembly of Pluronics: A critical review and relevant applications
Pluronics, alias poloxamers, are synthetic amphiphilic copolymers owning a triblock
structure with a central hydrophobic poly (propylene oxide)(PPO) segment linked to two …
structure with a central hydrophobic poly (propylene oxide)(PPO) segment linked to two …
Structural transitions in mixed phosphatidylcholine/pluronic micellar systems and their in vitro therapeutic evaluation for poorly water-soluble drug
The self-assemblies of phosphatidylcholine (PC) liposomes and Pluronic polymers with
varying compositions have been studied. The micellar transition formed in the mixed PC and …
varying compositions have been studied. The micellar transition formed in the mixed PC and …
Nanoscale Pluronic® micellar templates with varying% EO content for controlled drug release and cytotoxicity
This study investigates the self-assembly in ethylene oxide (EO)-propylene oxide (PO)-
based block copolymers (BCPs) with various molecular features like molecular weight …
based block copolymers (BCPs) with various molecular features like molecular weight …
Block Copolymer Encapsulation of Disarib, an Inhibitor of BCL2 for Improved Chemotherapeutic Potential
A chemical inhibitor of antiapoptotic protein, BCL2, known as Disarib, suffers poor solubility
in aqueous environments; thereby limiting its potential as a chemotherapeutic agent. To …
in aqueous environments; thereby limiting its potential as a chemotherapeutic agent. To …
Design, Development, and Evaluation of SA-F127:TPGS Polymeric Mixed Micelles for Improved Delivery of Glipizide Drug: In-vitro, Ex-vivo, and In-vivo …
The anti-diabetic glipizide (GLN) drug has notable pharmaceutical advantages, but poor
aqueous solubility restricts its wide applications. The present work was to develop a mixed …
aqueous solubility restricts its wide applications. The present work was to develop a mixed …
Amphiphilic pluronic F68 biomaterial augmented oral bioavailability and anticancer activity of genistein in lung cancer treatment
Many phyto‐based drugs available suffer from adverse effects due to their lack of water
solubility and poor bioavailability after oral administration. Genistein (Gen) is a plant‐derived …
solubility and poor bioavailability after oral administration. Genistein (Gen) is a plant‐derived …
Mixed Pluronic/lecithin micelles formulation for oral bioavailability of candesartan cilexetil drug: in vitro characterization and in vivo pharmacokinetic investigations
Objective This study aimed to develop a mixed polymeric micelle formulation incorporating
candesartan cilexetil (CAND) drug to enhance its oral bioavailability for the better treatment …
candesartan cilexetil (CAND) drug to enhance its oral bioavailability for the better treatment …
Produção, caracterização e avaliação biológica de nanopartículas carregadas com metotrexato e hidroxicloroquina para o tratamento da Artrite Reumatoide
TM Magne - 2023 - bdtd.uerj.br
Universidade do Estado do Rio de Janeiro Centro Biomédico Instituto de Biologia Roberto
Alcântara Gomes Taís Monteiro Magne P Page 1 Universidade do Estado do Rio de Janeiro …
Alcântara Gomes Taís Monteiro Magne P Page 1 Universidade do Estado do Rio de Janeiro …