Ubiquitin-modifying enzymes in thyroid cancer: Mechanisms and functions

X Xiong, BB Huang, Z Gan, W Liu, Y Xie, J Zhong… - Heliyon, 2024 - cell.com
Thyroid cancer is the most common malignant tumor of the endocrine system, and evidence
suggests that post-translational modifications (PTMs) and epigenetic alterations play an …

[HTML][HTML] VHL tumor suppressor as a novel potential candidate biomarker in papillary thyroid carcinoma

L Todorović, B Stanojević - Biomolecules and Biomedicine, 2023 - ncbi.nlm.nih.gov
Papillary thyroid carcinoma (PTC) is the most common type of endocrine cancer, with an
increasing incidence worldwide. The treatment of PTC is currently the subject of clinical …

Multi-omics profiling to assess signaling changes upon VHL restoration and identify putative VHL substrates in clear cell renal cell carcinoma cell lines

X Wang, J Hu, Y Fang, Y Fu, B Liu, C Zhang, S Feng… - Cells, 2022 - mdpi.com
The inactivation of von Hippel–Lindau (VHL) is critical for clear cell renal cell carcinoma
(ccRCC) and VHL syndrome. VHL loss leads to the stabilization of hypoxia-inducible factor α …

Исследование эффекторных молекул автономного и неавтономного влияния апоптоза Т-лимфоцитов в условиях «клеточного соседства» в культуре у …

ТЯ Абрамова, ЕА Блинова, ЕА Пашкина… - Медицинская …, 2022 - mimmun.ru
Аннотация Известно, что клеточный гомеостаз в организме поддерживается
процессами пролиферации и гибели клеток, при этом апоптоз является наиболее …

Studies of effector molecules exerting autonomous and nonautonomous influence of T lymphocyte apoptosis under the conditions of in vitro “cell neighborhood” in …

TY Abramova, EA Blinova, EA Pashkina… - Medical Immunology …, 2022 - mimmun.ru
Cellular homeostasis in the body is known to be maintained by the processes of cell
proliferation and death, whereas apoptosis is the most frequent and physiological,“silent” …

[PDF][PDF] AR Artificial Antagonist HC-1119 Regulated TNBC BT549 Cells Proliferation and Metastasis via PI3K/Akt/mTOR Signaling Pathway

Q Huang, Q Zhang, Q Ren, L Ma, X Li, T He, L Gan - 2022 - scholar.archive.org
Background: Triple negative breast cancer (TNBC) was a speci c refractory and aggressive
malignancy subtype of breast cancer with high mortality. Our study aimed to explore the …