Nanomedicine: A pragmatic approach for tackling melanoma skin cancer

VM Prajapat, S Mahajan, PG Paul, M Aalhate… - Journal of Drug Delivery …, 2023 - Elsevier
Melanoma is the most aggressive form of skin cancer and its annual incidence rates are
increasing globally. Though chemotherapy, radiotherapy, immunotherapy and targeted …

[HTML][HTML] Beyond the adverse effects of the systemic route: exploiting nanocarriers for the topical treatment of skin cancers

B da Silva Gomes, AC Paiva-Santos, F Veiga… - Advanced Drug Delivery …, 2024 - Elsevier
Skin cancer is a heterogeneous disease that can be divided into two main groups,
melanoma and nonmelanoma skin cancers. Conventional therapies for skin cancer have …

Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy

TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …

[HTML][HTML] LinTT1 peptide-functionalized liposomes for targeted breast cancer therapy

N d'Avanzo, G Torrieri, P Figueiredo, C Celia… - International journal of …, 2021 - Elsevier
Breast cancer, with around 2 million new cases in 2019, is the second most common cancer
worldwide and the second leading cause of cancer death among females. The aim of this …

Quality by design (QbD) assisted Fabrication & evaluation of Simvastatin loaded Nano-Enabled thermogel for melanoma therapy

P Famta, S Shah, V Fernandes, KC Kumar… - International journal of …, 2022 - Elsevier
Melanoma is a form of skin cancer that starts in melanocytes. Rampant chemo-resistance,
metastasis, and inability to cross the skin barriers and accumulate within the tumor …

Tailoring of novel bile salt stabilized vesicles for enhanced transdermal delivery of simvastatin: a new therapeutic approach against inflammation

ES Khafagy, BK Almutairy, AS Abu Lila - Polymers, 2023 - mdpi.com
Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory
effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing …

Ammonium glycyrrhizate skin delivery from ultradeformable liposomes: A novel use as an anti-inflammatory agent in topical drug delivery

A Barone, MC Cristiano, F Cilurzo, M Locatelli… - Colloids and Surfaces B …, 2020 - Elsevier
Glycyrrhiza glabra L. is a native plant of Central and South-Western Asia that is also diffused
in the Mediterranean area and contains several bioactive compounds such as: flavonoids …

QbD-driven development of intranasal lipid nanoparticles for depression treatment

C Vitorino, S Silva, F Gouveia, J Bicker, A Falcão… - European Journal of …, 2020 - Elsevier
Depression is a life-threatening psychiatric disorder and a multifactorial global public health
concern. Current pharmacological treatments present limited efficacy, and are associated …

Rutin-loaded nanovesicles for improved stability and enhanced topical efficacy of natural compound

MC Cristiano, A Barone, A Mancuso, D Torella… - Journal of functional …, 2021 - mdpi.com
Rutin is a natural compound with several pharmacological effects. Among these, antioxidant
activity is one of the best known. Despite its numerous benefits, its topical application is …

Karaya/gellan-gum-based bilayer films containing 3, 3′-diindolylmethane-loaded nanocapsules: a promising alternative to melanoma topical treatment

JB Reolon, CP Saccol, BF Osmari, DB Oliveira… - Pharmaceutics, 2023 - mdpi.com
This study aimed to incorporate nanocapsules containing 3, 3′-diindolylmethane (DIM)
with antitumor activity into a bilayer film of karaya and gellan gums for use in topical …