The vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor
(VEGFR) axis is indispensable in the process of angiogenesis and has been implicated as a …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

Angiogenesis assays based on in vitro capillary-like growth of endothelial cells (EC) are
widely used, either to evaluate the effect of anti-and pro-angiogenesis drugs of interest, or to …

Inflammatory response is a critical stage in typical wound healing. Although studies have
reported that some bioactive materials can modulate the polarization of macrophages to …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Objectives Epidermal growth factor plays a critical role in breast malignancies by enhancing
cell proliferation, invasion, angiogenesis and metastasis. Epithelial–mesenchymal transition …

Blood vessels that supply the inner portion of the retina are extensively reorganized during
development. The vessel regression, sprouting angiogenesis, vascular remodelling and …

The Notch pathway is a versatile regulator of cell fate specification, growth, differentiation,
and patterning processes in metazoan organisms. In the vertebrate cardiovascular system …

The formation of vascular lumens by endothelial cells is a critical step in the angiogenic
process that occurs during invasion and growth of the incipient vascular sprout. Once a …

In vivo, vascular endothelial growth factor (VEGF) and vascular endothelial cadherin (VE-
cadherin) co-regulate the dynamic organization of endothelial cells during vascular …