Background Serum albumin is the most abundant protein in the blood and cerebrospinal
fluid and plays a fundamental role in the distribution of essential transition metal ions in the …

Human serum albumin (HSA) is a monomeric, globular, multi-carrier and the most abundant
protein in the blood. HSA displays multiple ligand binding sites with extraordinary binding …

As a carrier of many biologically active compounds, blood is exposed to oxidants to a
greater extent than the intracellular environment. Serum albumin plays a key role in …

It has been reported that Cu (II) ions in human blood are bound mainly to serum albumin
(HSA), ceruloplasmin (CP), alpha-2-macroglobulin (α2M) and His, however, data for α2M …

Peptides and proteins with N‐terminal amino acid sequences NH2‐Xxx‐His (XH) and NH2‐
Xxx‐Zzz‐His (XZH) form well‐established high‐affinity CuII‐complexes. Key examples are …

Accumulation of the β‐amyloid (Aβ) peptide in extracellular senile plaques rich in copper
and zinc is a defining pathological feature of Alzheimer′ s disease (AD). The Aβ1–x (x …

Chiral coordination polymers and porous chiral MOFs have great potential as agents for
enantioselective separations, sensing, and catalysis due to their well-structured internal …

Copper ions have been proposed to play a central role in the amyloid cascade process
linked to the development of Alzheimer disease (AD). Involvement in both the amyloid-β (Aβ) …

A critical step in lipopolysaccharide (LPS) biogenesis involves flipping lipooligosaccharide,
an LPS precursor, from the cytoplasmic to the periplasmic leaflet of the inner membrane, an …

The designed" ATCUN" motif (amino-terminal copper and nickel binding site) is a replica of
naturally occurring ATCUN site found in many proteins/peptides, and an attractive platform …