Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations

S Chilvery, A Yelne, A Khurana, MA Saifi, S Bansod… - Phytomedicine, 2023 - Elsevier
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

Salvianolic acid C against acetaminophen‐induced acute liver injury by attenuating inflammation, oxidative stress, and apoptosis through inhibition of the Keap1/Nrf2 …

CT Wu, JS Deng, WC Huang, PC Shieh… - Oxidative Medicine …, 2019 - Wiley Online Library
Acetaminophen (APAP) overdose is one of the most common causes of drug‐induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

[HTML][HTML] Synthesis, characterizations, and RSM analysis of Citrus macroptera peel derived biochar for textile dye treatment

H Roy, TR Prantika, MH Riyad, S Paul… - South African Journal of …, 2022 - Elsevier
Textile wastewater discharging to the surface water body is a great concern because it
contains different pollutants such as dyes, organics, surfactants, inorganic salt and heavy …

[HTML][HTML] Association of antioxidant nutraceuticals and acetaminophen (paracetamol): Friend or foe?

M Abdel-Daim, AI Abushouk, R Reggi, NS Yarla… - journal of food and drug …, 2018 - Elsevier
Acetaminophen (paracetamol or APAP) is an analgesic and antipyretic drug that can induce
oxidative stress-mediated hepatotoxicity at high doses. Several studies reported that …

The modulatory effect of Moringa oleifera leaf extract on endogenous antioxidant systems and inflammatory markers in an acetaminophen-induced nephrotoxic mice …

G Karthivashan, AU Kura, P Arulselvan, NM Isa… - PeerJ, 2016 - peerj.com
N-Acetyl-p-Aminophenol (APAP), also known as acetaminophen, is the most commonly
used over-the counter analgesic and antipyretic medication. However, its overdose leads to …

Hepatoprotective Effect of Polyphenol‐Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen‐Induced Liver Injury in Mice

H Wu, G Zhang, L Huang, H Pang… - Oxidative medicine …, 2017 - Wiley Online Library
Folium Microcos (FM), the leaves of Microcos paniculata L., shows various biological
functions including antioxidant activity and α‐glucosidase inhibitory effect. However, its …

Effects of Inclusion of Different Doses of Persicaria odorata Leaf Meal (POLM) in Broiler Chicken Feed on Biochemical and Haematological Blood Indicators and Liver …

M Abdul Basit, A Abdul Kadir, TC Loh, S Abdul Aziz… - Animals, 2020 - mdpi.com
Simple Summary The frequent use of antimicrobial growth promoters (AGPs) in poultry feed
leads to antimicrobial resistance, resulting in a ban on their subtherapeutic use in food …

Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran

M Mondal, S Saha, C Sarkar, MS Hossen… - Chemical Research …, 2021 - ACS Publications
Citrus medica L. is rich in numerous vital bioactive constituents, though it is an underutilized
among the citrus genus. Therefore, the aim of the present investigation was to evaluate the …

Network pharmacology based investigation into the bioactive compounds and molecular mechanisms of Schisandrae Chinensis Fructus against drug-induced liver …

X Li, H Yang, J Xiao, J Zhang, J Zhang, M Liu… - Bioorganic …, 2020 - Elsevier
Objective To investigate the against Drug-induced liver injury ingredients and their
functional mechanisms in S. Chinensis Fructus. Methods Liquid chromatograph-mass …

Protective mechanism of turmeric (Curcuma longa) on carbofuran-induced hematological and hepatic toxicities in a rat model

MS Hossen, EM Tanvir, MB Prince, S Paul… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Turmeric (Curcuma longa L.[Zingiberaceae]) is used in the treatment of a
variety of conditions including pesticide-induced toxicity. Objective: The study reports the …