High-risk atherosclerosis and metabolic phenotype: the roles of ectopic adiposity, atherogenic dyslipidemia, and inflammation

K Lechner, AL McKenzie, N Kränkel… - … syndrome and related …, 2020 - liebertpub.com
Current algorithms for assessing risk of atherosclerotic cardiovascular disease (ASCVD)
and, in particular, the reliance on low-density lipoprotein (LDL) cholesterol in conditions …

Body mass index and association with cardiovascular outcomes in patients with stable coronary heart disease–a stability substudy

C Held, N Hadziosmanovic, PE Aylward… - Journal of the …, 2022 - Am Heart Assoc
BACKGROUND The obesity paradox states that patients with higher body mass index (BMI)
and cardiovascular disease may experience better prognosis. However, this is less clear in …

Omega-3 fatty acid blood levels are inversely associated with cardiometabolic risk factors in HFpEF patients: The Aldo-DHF randomized controlled trial

K Lechner, J Scherr, E Lorenz, B Lechner… - Clinical Research in …, 2022 - Springer
Objectives To evaluate associations of omega-3 fatty acid (O3-FA) blood levels with
cardiometabolic risk markers, functional capacity and cardiac function/morphology in …

Waist-to-height ratio and metabolic phenotype compared to the Matsuda index for the prediction of insulin resistance

K Lechner, B Lechner, A Crispin, PEH Schwarz… - Scientific Reports, 2021 - nature.com
Current screening algorithms for type 2 diabetes (T2D) rely on fasting plasma glucose (FPG)
and/or HbA1c. This fails to identify a sizeable subgroup of individuals in early stages of …

Saturated fatty acid blood levels and cardiometabolic phenotype in patients with HFpEF: a secondary analysis of the Aldo-DHF trial

K Lechner, C von Schacky, J Scherr, E Lorenz, M Bock… - Biomedicines, 2022 - mdpi.com
Background: Circulating long-chain (LCSFAs) and very long-chain saturated fatty acids
(VLSFAs) have been differentially linked to risk of incident heart failure (HF). In patients with …

De Novo Lipogenesis-Related Monounsaturated Fatty Acids in the Blood Are Associated with Cardiovascular Risk Factors in HFpEF Patients

M Bock, C von Schacky, J Scherr, E Lorenz… - Journal of Clinical …, 2023 - mdpi.com
De novo lipogenesis (DNL)-related monounsaturated fatty acids (MUFAs) in the blood are
associated with incident heart failure (HF). This observation's biological plausibility may be …

Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men

K Lechner, S Heel, M Uhr, T Dose, F Holsboer… - Naunyn-Schmiedeberg's …, 2023 - Springer
Abstract Treatment with mirtazapine, a widely prescribed antidepressant, has been linked to
weight gain and dyslipidemia. Whether dyslipidemia occurs secondary to increased appetite …

Trans-fatty acid blood levels of industrial but not natural origin are associated with cardiovascular risk factors in patients with HFpEF: A secondary analysis of the Aldo …

K Lechner, M Bock, C von Schacky, J Scherr… - Clinical Research in …, 2023 - Springer
Background Industrially processed trans-fatty acids (IP-TFA) have been linked to altered
lipoprotein metabolism, inflammation and increased NT-proBNP. In patients with heart …

Association of the Atherogenic Index of Plasma with C-Reactive Protein and Urinary Albumin Excretion in a Normotensive Nondiabetic Population

S Akıncı, A Çoner, E Akbay, A Adar… - … and Related Disorders, 2022 - liebertpub.com
Background: The atherogenic index of plasma (AIP) is an indicator of atherogenic
dyslipidemia and is significantly associated with the development of atherosclerotic …

Estudo da Prevalência da Síndrome Metabólica e da Contribuição Relativa dos Seus Componentes em Indivíduos Adultos do Distrito de Bragança

JE de Araújo Teixeria - 2022 - search.proquest.com
Introdução: A compreensão do fator de ponderação de cada componente na alteração do
estado da Síndrome Metabólica (SM) pode ajudar a prever a sua progressão para as …