GatekeepR: an R Shiny application for the identification of nodes with high dynamic impact in Boolean networks
Motivation Boolean networks can serve as straightforward models for understanding
processes such as gene regulation, and employing logical rules. These rules can either be …
processes such as gene regulation, and employing logical rules. These rules can either be …
Logical modelling of molecular crosstalks for the prediction of complex phenotypes
N Ikonomi - 2023 - oparu.uni-ulm.de
Abstract Systems biology investigates the understanding of complex biological processes,
such as ageing or cancer, by integrating a holistic view, which is mostly unconsidered when …
such as ageing or cancer, by integrating a holistic view, which is mostly unconsidered when …
Classical and quantum-mechanical algorithmic approaches for exploring the dynamics of Boolean networks
F Weidner - 2024 - oparu.uni-ulm.de
Boolean networks allow for the construction of dynamical models of biological processes
such as the cell cycle, cellular differentiation, ageing or diseases such as cancer. The …
such as the cell cycle, cellular differentiation, ageing or diseases such as cancer. The …
Boolean network modeling and its integration with experimental read-outs: An interdisciplinary presentation using a leukemia model
The limited availability of suitable animal models and cell lines often impedes experimental
cancer research. Wet-laboratory experiments are also time-consuming and cost-intensive. In …
cancer research. Wet-laboratory experiments are also time-consuming and cost-intensive. In …
Networks to Simulate the Development of Interacting Systems in Molecular Biology
Biological systems must adapt to a variety of changing circumstances over the course of
lifetime. They therefore rely on complex and robust mechanisms. This includes the …
lifetime. They therefore rely on complex and robust mechanisms. This includes the …
[PDF][PDF] Methods for control strategy identification in Boolean networks
L Cifuentes Fontanals - 2023 - pure.mpg.de
Understanding control mechanisms in biological processes plays a crucial role in the
development of potential applications in the fields of bioengineering and medicine. The …
development of potential applications in the fields of bioengineering and medicine. The …
A First Glance on Coevolution of Boolean Networks to Simulate the Development of Interacting Systems in Molecular Biology
Biological systems must adapt to a variety of changing circumstances over the course of
lifetime. They therefore rely on complex and robust mechanisms. This includes the …
lifetime. They therefore rely on complex and robust mechanisms. This includes the …