Nucleic acid amplification techniques have always been one of the hot spots of research,
especially in the outbreak of COVID-19. From the initial polymerase chain reaction (PCR) to …

Conspectus The development of robust methods allowing the precise detection of specific
nucleic acid sequences is of major societal relevance, paving the way for significant …

Circle-to-circle amplification (C2CA) is a specific and precise cascade nucleic acid
amplification method consisting of more than one round of padlock probe ligation and rolling …

The field of centrifugal microfluidics has experienced tremendous growth during the past 15
years, especially in applications such as lab-on-a-disc (LoD) diagnostics. The strength of …

Rolling circle amplification (RCA) of DNA can be considered as a great alternative to the
gold standard polymerase chain reaction (PCR), especially during this pandemic period …

We demonstrate a novel digital microfluidic nucleic acid amplification concept which is
based on padlock probe mediated DNA detection and isothermal circle-to-circle …

Crimean-Congo hemorrhagic fever (CCHF) is an expanding tick-borne hemorrhagic disease
with increasing human and animal health impact. Immense knowledge was gained over the …

Crimean-Congo hemorrhagic fever (CCHF) is a highly contagious viral tick-borne disease
with case-fatality rates as high as 50%. We describe a collaborative evaluation of the …

We demonstrate a nanoparticle-based assay for the detection of bacteria causing urinary
tract infections in patient samples with a total assay time of 4 h. This time is significantly …

Crimean-Congo hemorrhagic fever virus (CCHFV; genus Nairovirus) is an extremely
pathogenic member of the Bunyaviridae family. Since handling of the virus requires a …