The role of the prostate in male fertility, health and disease
P Verze, T Cai, S Lorenzetti - Nature Reviews Urology, 2016 - nature.com
Ejaculation is a synchronized cascade of events that has the ultimate goal of activating
sperm and enabling them to reach an egg for fertilization. The seminal plasma contains a …
sperm and enabling them to reach an egg for fertilization. The seminal plasma contains a …
Effects of aging on the male reproductive system
The study aims to discuss the effects of aging on the male reproductive system. A systematic
review was performed using PubMed from 1980 to 2014. Aging is a natural process …
review was performed using PubMed from 1980 to 2014. Aging is a natural process …
Single-cell analysis of human testis aging and correlation with elevated body mass index
X Nie, SK Munyoki, M Sukhwani, N Schmid, A Missel… - Developmental cell, 2022 - cell.com
Aging men display reduced reproductive health; however, testis aging is poorly understood
at the molecular and genomic levels. Here, we utilized single-cell RNA-seq to profile over …
at the molecular and genomic levels. Here, we utilized single-cell RNA-seq to profile over …
A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic …
CG Stief, H Porst, D Neuser, M Beneke, E Ulbrich - European urology, 2008 - Elsevier
INTRODUCTION: Benign prostatic hyperplasia (BPH) is associated with bothersome lower
urinary tract symptoms (LUTS) and reduced patient quality of life (QoL). Phosphodiesterase …
urinary tract symptoms (LUTS) and reduced patient quality of life (QoL). Phosphodiesterase …
The role of inflammation in lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) and its potential impact on medical therapy
V Ficarra, M Rossanese, M Zazzara, G Giannarini… - Current urology …, 2014 - Springer
A chronic prostatic inflammation seems to play a crucial role in benign prostatic hyperplasia
(BPH) pathogenesis and progression. Therefore, inflammation could represent a new …
(BPH) pathogenesis and progression. Therefore, inflammation could represent a new …
Molecular control of luteal secretion of progesterone
GD Niswender - Reproduction, 2002 - rep.bioscientifica.com
Cholesterol provided by low-or high-density lipoprotein is the precursor for biosynthesis of
progesterone. Once inside the cell, cholesterol can be used for steroidogenesis or esterified …
progesterone. Once inside the cell, cholesterol can be used for steroidogenesis or esterified …
[HTML][HTML] A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell …
The testis is pivotal for male reproduction, and its progressive functional decline in aging is
associated with infertility. However, the regulatory mechanism underlying primate testicular …
associated with infertility. However, the regulatory mechanism underlying primate testicular …
ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma
N Sampson, R Koziel, C Zenzmaier… - Molecular …, 2011 - academic.oup.com
Stromal remodeling, in particular fibroblast-to-myofibroblast differentiation, is a hallmark of
benign prostatic hyperplasia (BPH) and solid tumors, including prostate cancer (PCa) …
benign prostatic hyperplasia (BPH) and solid tumors, including prostate cancer (PCa) …
Advanced paternal age and reproductive outcome
Z Wiener-Megnazi, R Auslender… - Asian journal of …, 2011 - pmc.ncbi.nlm.nih.gov
Women have been increasingly delaying the start of motherhood in recent decades. The
same trend is seen also for men. The influence of maternal age on fertility, chromosomal …
same trend is seen also for men. The influence of maternal age on fertility, chromosomal …
Oxidative stress-related aging: a role for prostate cancer?
Prostate cancer has the highest prevalence of any non-cutaneous cancer in the human body
and essentially all men with circulating androgens will develop microscopic prostate cancer …
and essentially all men with circulating androgens will develop microscopic prostate cancer …