Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Osteoarthritis (OA), is a major cause of severe joint pain, physical disability and quality of life
impairment in the aging population across the developed and developing world. Increased …

Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

Objectives Evidences have suggested that the metabolic function is the key regulator to the
fate of MSCs, but its function in senescence of MSC and the underlying mechanism is …

Mesenchymal stromal cells (MSCs) have shown to be a promising tool in cell therapies to
treat different conditions. Several pre-clinical and clinical studies have proved that the …

Abstract Background Mesenchymal stem cells (MSCs)-based treatment strategy has shown
promise in bolstering the healing process of chronic wounds in diabetic patients, who are at …

Mesenchymal stem cells (MSCs) are known to play important roles in the repair of lost or
damaged tissues and immunotolerance. On the other hand, aging is known to impair MSC …

Background Periodontal ligament stem cells (PDLSCs) have many applications in the field
of cytotherapy, tissue engineering, and regenerative medicine. However, the effect of age on …

Abstract Background Mesenchymal stem cells (MSCs) have been widely used in
cytotherapy and tissue engineering due to their immunosuppressive ability and regenerative …

In humans, sexual dimorphism can manifest in many ways and it is widely studied in several
knowledge fields. It is increasing the evidence that also cells differ according to sex, a …