Metalloenzymes catalyze a variety of reactions using a limited number of natural amino
acids and metallocofactors. Therefore, the environment beyond the primary coordination …

Protein design has come of age, but how will it mature? In the 1980s and the 1990s, the
primary motivation for de novo protein design was to test our understanding of the …

One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

Wound repair, as one of the most intricate biological mechanisms, is essential to ensure the
formation and integrity of the skin barrier. However, multiple factors can cause delays and …

Signal amplification strategies are widely used for improving the sensitivity of lateral flow
immunoassays (LFiAs). Herein, the artificial miniaturized peroxidase Fe (III)‐MimochromeVI …

Enzymes are versatile and efficient biological catalysts that drive numerous cellular
processes, motivating the development of enzyme design approaches to tailor catalysts for …

The generation of catalytically active metalloproteins inside living mammalian cells is a
major research challenge at the interface between catalysis and cell biology. Herein we …

Heme–copper oxidases (HCO), nitric oxide reductases (NOR), and sulfite reductases (SiR)
catalyze the multi-electron and multi-proton reductions of O2, NO, and SO32−, respectively …

The utilization of materials in medical implants, serving as substitutes for non-functional
biological structures, supporting damaged tissues, or reinforcing active organs, holds …

Environmental security is closely related to public health. Aromatic pollutants constitute a
class of hazardous environmental chemicals, such as halophenols and polycyclic aromatic …