Orofacial clefts embryology, classification, epidemiology, and genetics

G Nasreddine, J El Hajj… - … Research/Reviews in …, 2021 - Elsevier
Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Genetics of nonsyndromic orofacial clefts

F Rahimov, A Jugessur… - The Cleft palate …, 2012 - journals.sagepub.com
With an average worldwide prevalence of approximately 1.2/1000 live births, orofacial clefts
are the most common craniofacial birth defects in humans. Like other complex disorders …

Unraveling human cleft lip and palate research

AR Vieira - Journal of dental research, 2008 - journals.sagepub.com
The focus of this work is to highlight the most recent advances in the understanding of cleft
lip and palate occurrence. Information regarding research on long-term outcomes, genes …

Human genetic factors in nonsyndromic cleft lip and palate: an update

F Carinci, L Scapoli, A Palmieri, I Zollino… - International journal of …, 2007 - Elsevier
Nonsyndromic cleft lip and/or palate (or orofacial cleft, OFC) is a malformation characterized
by an incomplete separation between nasal and oral cavities without any associated …

The etiopathogenesis of cleft lip and cleft palate: usefulness and caveats of mouse models

A Gritli‐Linde - Current topics in developmental biology, 2008 - Elsevier
Cleft lip and cleft palate are frequent human congenital malformations with a complex
multifactorial etiology. These orofacial clefts can occur as part of a syndrome involving …

[HTML][HTML] Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts

AR Vieira, TG McHenry, S Daack-Hirsch, JC Murray… - Genetics in …, 2008 - Elsevier
Purpose We revisited 42 families with two or more cleft-affected siblings who participated in
previous studies. Complete dental information was collected to test the hypothesis that …

Current concepts in genetics of nonsyndromic clefts

J Murthy, L Bhaskar - Indian Journal of Plastic Surgery, 2009 - thieme-connect.com
Nonsyndromic cleft lip and palate is a complex genetic disorder with variable phenotype,
largely attributed to the interactions of the environment and multiple genes, each potentially …

Novel MSX1 mutation in a family with autosomal-dominant hypodontia of second premolars and third molars

A Mostowska, B Biedziak, PP Jagodzinski - Archives of oral biology, 2012 - Elsevier
OBJECTIVE: Tooth agenesis is the most common developmental anomaly of the human
dentition, with aetiology involving both genetic and environmental factors. The aim of the …

Molecular signaling along the anterior–posterior axis of early palate development

TM Smith, S Lozanoff, PP Iyyanar… - Frontiers in physiology, 2013 - frontiersin.org
Cleft palate is a common congenital birth defect in humans. In mammals, the palatal tissue
can be distinguished into anterior bony hard palate and posterior muscular soft palate that …

Genotype and haplotype analysis of WNT genes in non‐syndromic cleft lip with or without cleft palate

A Mostowska, KK Hozyasz, B Biedziak… - European Journal of …, 2012 - Wiley Online Library
Mostowska A, Hozyasz KK, Biedziak B, Wojcicka P, Lianeri M, Jagodzinski PP. Genotype
and haplotype analysis of WNT genes in non‐syndromic cleft lip with or without cleft palate …