Catalytic formation of a regio-and enantioselective C–F bond chiral center from readily
available alkenes is a crucial goal, yet it continues to pose significant challenges in organic …

Transition metal-catalyzed enantioselective hydroamination of 1, 3-dienes provides a direct
methodology for the construction of chiral allylamines. So far, all of the reported examples …

We report herein the acid-catalyzed regioselective remote heteroarylation and reductive
alkylation of alkenes. Various alkenes, including mono-, di-, and tri-substituted alkenes and …

We herein describe a Ni-catalyzed formal hydroamidation of readily available α, β-
unsaturated carbonyl compounds to afford valuable chiral β-amino acid derivatives (up to> …

The reactivity of allenes has historically been limited with no previous examples of their
hydroalkylation using diazo compounds in any transition-metal catalytic framework. In this …

We have developed a nickel-catalysed regio-and stereoselective hydrocyanation of
alkynoates that gives syn-β-cyanoalkenes. DFT calculations suggest that a favored transition …

Herein, we report a novel Al compound supported by a NacNac ligand that facilitates the anti-
Markovnikov hydroamination of aromatic alkenes and primary amines. This represents the …

Abstract A nickel-hydride (NiH)-catalyzed migratory and nonmigratory hydroalkylation
reaction of 2-alkenyl azaarenes with alkyl iodines has been established through strategic …

Cyclopropylmethyl sulfides react with N‐fluorosulfonimide (NFSI) or molecular iodine,
enabling C− S cleavage to generate cyclopropylcarbinyl cations, which evolve through …

While enantioselective hydrofluorination methods for activated alkenes represent a notable
advance, the resultant enantiomeric excesses remain largely moderate, indicating the …