Despite many available approaches for transdermal drug delivery, patient compliance and
drug targeting at the desired concentration are still concerns for effective therapies. Precise …

Introduction: Present article reviews solid dispersion (SD) technologies and other patented
inventions in the area of pharmaceutical SDs, which provide stable amorphous SDs. Areas …

Although zein is a natural protein derived from corn, it has attracted much interest in
pharmaceutical and biomedical sciences. Recent remarkable investigations on the use of …

In addition to a number of highly soluble drugs, most new chemical entities under
development are poorly water-soluble drugs generally characterized by an insufficient …

Physicochemical characterization is a crucial step for the successful development of solid
dispersions, including the determination of drug crystallinity and molecular interactions …

In the recent years, coamorphous systems, containing an active pharmaceutical ingredient
(API) and a small molecule coformer have appeared as alternatives to the use of either …

The formation of co-amorphous by combining low molecular weight compounds with drugs
is a relatively new technology in the pharmaceutical field, which can significantly improve …

The objective of this study was to formulate aripiprazole (ARI)-loaded pH-modulated solid
dispersions (SD) to enhance solubility, dissolution, and bioavailability via hot-melt extrusion …

Excipients are generally pharmacologically inert, but can interact with drugs in the dosage
form and the physiological factors at the site of absorption to affect the bioavailability of a …

Quality by design (QbD) principles were implemented to understand the product and
process variables of sonoprecipitation technique, for preparation of eprosartan mesylate …