A review of seizures and epilepsy following traumatic brain injury

S Fordington, M Manford - Journal of neurology, 2020 - Springer
Traumatic brain injury (TBI) is one of the commonest presentations to emergency
departments and is associated with seizures carrying different significance at different …

The aetiologies of epilepsy

S Balestrini, A Arzimanoglou, I Blümcke… - Epileptic …, 2021 - Wiley Online Library
The identification of the aetiology of a patient's epilepsy is instrumental in the diagnosis,
prognostic counselling and management of the epilepsies. Indeed, the aetiology can be …

Identification of clinically relevant biomarkers of epileptogenesis—a strategic roadmap

M Simonato, DV Agoston, A Brooks-Kayal… - Nature Reviews …, 2021 - nature.com
Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …

Traumatic brain injury: Mechanisms, manifestations, and visual sequelae

SH Rauchman, A Zubair, B Jacob… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …

Temporal proteomics of human cerebrospinal fluid after severe traumatic brain injury

SR Shultz, AD Shah, C Huang, LK Dill… - Journal of …, 2022 - Springer
The pathophysiology of traumatic brain injury (TBI) requires further characterization to fully
elucidate changes in molecular pathways. Cerebrospinal fluid (CSF) provides a rich …

Risk factors and incidence of epilepsy after severe traumatic brain injury

M Pease, J Gonzalez‐Martinez, A Puccio… - Annals of …, 2022 - Wiley Online Library
We determined the incidence of post‐traumatic epilepsy after severe traumatic brain injury.
Of 392 patients surviving to discharge, cumulative incidence of post‐traumatic epilepsy was …

Post-traumatic epilepsy and comorbidities: advanced models, molecular mechanisms, biomarkers, and novel therapeutic interventions

VM Golub, DS Reddy - Pharmacological reviews, 2022 - ASPET
Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …

Neuroinflammatory mechanisms of post-traumatic epilepsy

S Mukherjee, GM Arisi, K Mims, G Hollingsworth… - Journal of …, 2020 - Springer
Background Traumatic brain injury (TBI) occurs in as many as 64–74 million people
worldwide each year and often results in one or more post-traumatic syndromes, including …

Antiepileptic Drugs as Potential Dementia Prophylactics Following Traumatic Brain Injury

LF Locskai, H Alyenbaawi… - Annual review of …, 2024 - annualreviews.org
Seizures and other forms of neurovolatility are emerging as druggable prodromal
mechanisms that link traumatic brain injury (TBI) to the progression of later dementias. TBI …

Modelling traumatic brain injury and posttraumatic epilepsy in rodents

RD Brady, PM Casillas-Espinosa, DV Agoston… - Neurobiology of …, 2019 - Elsevier
Posttraumatic epilepsy (PTE) is one of the most debilitating and understudied consequences
of traumatic brain injury (TBI). It is challenging to study the effects, underlying …