Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification

C Bergom, JA Bradley, AK Ng, P Samson, C Robinson… - Cardio Oncology, 2021 - jacc.org
Radiation therapy is an important component of cancer therapy for many malignancies. With
improvements in cardiac-sparing techniques, radiation-induced cardiac dysfunction has …

Risk factors of fluoropyrimidine induced cardiotoxicity among cancer patients: a systematic review and meta-analysis

C Li, S Ngorsuraches, C Chou, L Chen… - Critical Reviews in …, 2021 - Elsevier
Cancer patients experienced an increased risk of cardiotoxicity during fluoropyrimidine-
based chemotherapy (5-fluorouracil or capecitabine). We searched PubMed, PsycINFO, IPA …

Automatic delineation of cardiac substructures using a region‐based fully convolutional network

J Harms, Y Lei, S Tian, NS McCall, KA Higgins… - Medical …, 2021 - Wiley Online Library
Purpose Radiation dose to specific cardiac substructures, such as the atria and ventricles,
has been linked to post‐treatment toxicity and has shown to be more predictive of these …

Cardiac dose reduction using deep inspiratory breath hold (DIBH) in radiation treatment of left sided breast cancer patients with breast conservation surgery and …

S Misra, A Mishra, P Lal, R Srivastava, M Verma… - Journal of Medical …, 2021 - Elsevier
Purpose Deep inspiration breath hold (DIBH) reduces heart and pulmonary doses during left-
sided breast radiation therapy (RT); however, there is limited information whether the …

Evaluation of cardiotoxicity in HER-2-positive breast cancer patients treated with radiation therapy and trastuzumab

B Bachir, S Anouti, J Abi Jaoude, M Kayali… - International Journal of …, 2022 - Elsevier
Purpose Trastuzumab is associated with cardiac dysfunction in patients with human
epidermal growth factor receptor 2 (HER-2)–positive breast cancer. The current study …

Radiation therapy in the thoracic region: Radio-induced cardiovascular disease, cardiac delineation and sparing, cardiac dose constraints, and cardiac implantable …

C Petit, A Escande, T Sarrade, L Vaugier, Y Kirova… - Cancer …, 2023 - Elsevier
Radiation therapy in the thoracic region may deliver incidental ionizing radiation to the
surrounding healthy structures, including the heart. Radio-induced heart toxicity has long …

[HTML][HTML] Organ-sparing techniques and dose-volume constrains used in breast cancer radiation therapy–Results from European and Latin American surveys

ME Chirilă, F Kraja, GN Marta, WFPN Junior… - Clinical and …, 2024 - Elsevier
Background Advances in local and systemic therapies have improved the outcomes of
patients with breast cancer (BC), leading to a possible increased risk for postoperative …

Cardiotoxicity related to radiation therapy

S Shoukat, D Zheng, SW Yusuf - Cardiology Clinics, 2019 - cardiology.theclinics.com
In recent decades, cancer treatment modalities have advanced significantly, with radiation
therapy (RT) becoming an essential aspect of treatment of many malignancies, including …

Dose-volume histogram analysis of knowledge-based volumetric-modulated arc therapy planning in postoperative breast cancer irradiation

E Inoue, H Doi, H Monzen, M Tamura, M Inada… - in vivo, 2020 - iv.iiarjournals.org
Background/Aim: We evaluated the dosimetric profiles of manually generated volumetric-
modulated arc therapy (VMAT) plans and performance of a commercial knowledge-based …

Advances in Screening for Radiation-Associated Cardiotoxicity in Cancer Patients

W Schiffer, LN Pedersen, M Lui, C Bergom… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Radiation is foundational to the treatment of cancer and
improves overall survival. Yet, it is important to recognize the potential cardiovascular effects …