Advances in areas that include genomics, systems biology, protein structure determination
and artificial intelligence provide new opportunities for target-based antibacterial drug …

There is a lack of new antibiotics to combat drug-resistant bacterial infections that
increasingly threaten global health. The current pipeline of clinical-stage antimicrobials is …

Antibiotic resistance has led to an increase in the number of patient hospitalizations and
deaths. The situation for gram-negative bacteria is especially dire as the last new class of …

The outer membrane of Gram-negative bacteria is closely related to the pathogenicity and
drug resistance of bacteria. Outer membrane proteins (OMPs) are a class of proteins with …

The β-barrel assembly machinery (BAM) is a multimeric protein complex responsible for the
folding of outer membrane proteins in gram-negative bacteria. It is essential for cell survival …

Diderm bacteria employ β‐barrel outer membrane proteins (OMPs) as their first line of
communication with their environment. These OMPs are assembled efficiently in the …

Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide health issue. The
innovation gap in discovering new antibiotics has remained a significant hurdle in …

In the fight against bacterial infections, particularly those caused by multi‐resistant
pathogens, the need for new antibacterials is undoubted in scientific communities. and is by …