Thrombotic microangiopathy (TMA) is defined by specific clinical characteristics, including
microangiopathic hemolytic anemia, thrombocytopenia, and pathologic evidence of …

Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …

In recent years, a dynamic development of oncology has been observed, resulting from the
increasingly frequent occurrence of neoplasms and therefore, increasing population of …

Aims Gemcitabine has been associated with thrombotic microangiopathy (TMA). We
conducted a national retrospective study of gemcitabine‐associated TMA (G‐TMA). Methods …

Background This phase I trial evaluated the safety and tolerability of milciclib, an inhibitor of
multiple cyclin-dependent kinases and tropomycin receptor kinase A, in combination with …

Histone deacetylase (HDAC) is overexpressed in multiple cancers including pancreatic
cancer (PC). However, the effects of histone deacetylase inhibitor (HDACi) on apoptosis and …

Simple Summary Anticancer nucleoside analogs are promising treatments that often result
in damaging toxicities and therefore ineffective treatment. Mechanisms of this are not well …

Bevacizumab (Avastin) is a recombinant humanized monoclonal antibody used for the
management of various solid malignancies including colorectal, lung, brain, renal, and …

Due to early onset of local invasion and distant metastasis, pancreatic cancer is the most
lethal human malignant tumor, with a 5 year survival rate of less than 5%. As a effective …

We present here the case of a 39-year-old man with metastatic pancreatic carcinoma
receiving chemotherapy with the combination of gemcitabine and nab-paclitaxel as part of a …