The impact of obesity on doravirine exposure in people with HIV
L Zino, LPM van Bussel, R Greupink, M Marneef… - AIDS, 2024 - journals.lww.com
Obesity incidence is increasing among people with HIV. Doravirine is a recommended first-
line antiretroviral drug in many countries with no data from people with obesity. This study …
line antiretroviral drug in many countries with no data from people with obesity. This study …
Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept
JEM van der Heijden, M de Hoop-Sommen… - Frontiers in …, 2024 - frontiersin.org
Introduction Critically ill patients show large variability in drug disposition due to eg, age,
size, disease and treatment modalities. Physiologically-based pharmacokinetic (PBPK) …
size, disease and treatment modalities. Physiologically-based pharmacokinetic (PBPK) …