A wide range of missing imputation approaches in longitudinal data: a simulation study and real data analysis

M Jahangiri, A Kazemnejad, KS Goldfeld… - BMC Medical Research …, 2023 - Springer
Background Missing data is a pervasive problem in longitudinal data analysis. Several
single-imputation (SI) and multiple-imputation (MI) approaches have been proposed to …

Cohort profile update: Tehran cardiometabolic genetic study

MS Daneshpour, M Akbarzadeh, H Lanjanian… - European Journal of …, 2023 - Springer
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study
that conducts periodic follow-ups. TCGS has created a comprehensive database comprising …

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

H Toh, C Yang, G Formenti, K Raja, L Yan, A Tracey… - BMC biology, 2022 - Springer
Abstract Background The Nile rat (Avicanthis niloticus) is an important animal model
because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet …

Should Glucokinase be Given a Chance in Diabetes Therapeutics? A Clinical-Pharmacological Review of Dorzagliatin and Lessons Learned So Far

U Kaur, BK Pathak, TJ Meerashahib… - Clinical Drug …, 2024 - Springer
Despite advances in the management of type 2 diabetes mellitus (T2DM), one-third of
patients with diabetes do not achieve the desired glycemic goal. Considering this …

Early prediction for prediabetes and type 2 diabetes using the genetic risk score and oxidative stress score

X Huang, Y Han, K Jang, M Kim - Antioxidants, 2022 - mdpi.com
We aimed to use a genetic risk score (GRS) constructed with prediabetes and type 2
diabetes-related single nucleotide polymorphisms (SNPs) and an oxidative stress score …

Unique genetic variants of lean nonalcoholic fatty liver disease: a retrospective cohort study

J Li, N Wu, Y Yang, X Zhai, F Yuan, F Zhang… - BMC Endocrine …, 2023 - Springer
We investigated the prevalence and clinical metabolic characteristics of lean nonalcoholic
fatty liver disease (NAFLD) in an elderly Chinese population and assessed the relevance of …

Genome-wide association study for metabolic syndrome reveals APOA5 single nucleotide polymorphisms with multilayered effects in Koreans

YJ Park, S Moon, J Choi, J Kim, HJ Kim, HY Son… - Lipids in Health and …, 2024 - Springer
Background and purpose Genome-wide association studies (GWAS) of metabolic syndrome
(MetS) have predominantly focused on non-Asian populations, with limited representation …

Interaction between genetic risk score and dietary fat intake on lipid-related traits in Brazilian young adults

R Wuni, H Amerah, S Ammache, NT Cruvinel… - British Journal of …, 2024 - cambridge.org
The occurrence of dyslipidaemia, which is an established risk factor for cardiovascular
diseases, has been attributed to multiple factors including genetic and environmental …

GlycA and CRP Are Genetically Correlated: Insight into the Genetic Architecture of Inflammageing

M Kasher, MB Freidin, FMK Williams, G Livshits… - Biomolecules, 2024 - mdpi.com
Inflammageing is a condition of perpetual low-grade inflammation induced by ageing.
Inflammageing may be predicted by the C-reactive protein (CRP) or by a recently described …

Whole-exome sequencing reveals novel variants of monogenic diabetes in Tunisia: impact on diagnosis and healthcare management

N Kheriji, H Dallali, I Gouiza, M Hechmi… - Frontiers in …, 2023 - frontiersin.org
Introduction: Monogenic diabetes (MD) accounts for 3%–6% of all cases of diabetes. This
prevalence is underestimated due to its overlapping clinical features with type 1 and type 2 …