Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine
Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum originated from at least six
foci in South America, Asia, and Oceania. Malaria parasites from these locations exhibit …
foci in South America, Asia, and Oceania. Malaria parasites from these locations exhibit …
[HTML][HTML] Changing patterns of Plasmodium blood-stage infections in the Wosera region of Papua New Guinea monitored by light microscopy and high throughput PCR …
LJ Kasehagen, IVO Mueller… - The American journal …, 2006 - ncbi.nlm.nih.gov
Abstract In Papua New Guinea (PNG), complex patterns of malaria commonly include single
and mixed infections of Plasmodium falciparum, P. vivax, P. malariae, and P. ovale. Here …
and mixed infections of Plasmodium falciparum, P. vivax, P. malariae, and P. ovale. Here …
Discordant Patterns of Genetic Variation at Two Chloroquine Resistance Loci in Worldwide Populations of the Malaria Parasite Plasmodium falciparum
RK Mehlotra, G Mattera, MJ Bockarie… - Antimicrobial agents …, 2008 - Am Soc Microbiol
Mutations in the chloroquine resistance (CQR) transporter gene of Plasmodium falciparum
(Pf crt; chromosome 7) play a key role in CQR, while mutations in the multidrug resistance …
(Pf crt; chromosome 7) play a key role in CQR, while mutations in the multidrug resistance …
Research challenges and gaps in malaria knowledge in Papua New Guinea
Taking into consideration the relative number of people living in Papua New Guinea the
burden of malaria in this country is among the highest in Asia and the Pacific region. This …
burden of malaria in this country is among the highest in Asia and the Pacific region. This …
In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea
RPM Wong, D Lautu, L Tavul… - Tropical Medicine & …, 2010 - Wiley Online Library
Objective Recent clinical studies have shown high rates of malaria treatment failure in
endemic areas of Papua New Guinea (PNG), necessitating a change of treatment from …
endemic areas of Papua New Guinea (PNG), necessitating a change of treatment from …
Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea
M Sekihara, SI Tachibana, M Yamauchi, S Yatsushiro… - Malaria Journal, 2018 - Springer
Abstract Background Chloroquine treatment for Plasmodium falciparum has been
discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal …
discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal …
Mutant pfcrt "SVMNT" haplotype and wild type pfmdr1 "N86" are endemic in Plasmodium vivax dominated areas of India under high chloroquine exposure
PK Mallick, H Joshi, N Valecha, SK Sharma, A Eapen… - Malaria journal, 2012 - Springer
Background Chloroquine resistance (CQR) phenotype in Plasmodium falciparum is
associated with mutations in pfcrt and pfmdr-1 genes. Mutations at amino acid position 72 …
associated with mutations in pfcrt and pfmdr-1 genes. Mutations at amino acid position 72 …
Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance
Background Molecular monitoring of parasite resistance has become an important
complementary tool in establishing rational anti-malarial drug policies. Community surveys …
complementary tool in establishing rational anti-malarial drug policies. Community surveys …
Molecular Assessment of Plasmodium falciparum Resistance to Antimalarial Drugs in Papua New Guinea Using an Extended Ligase Detection Reaction Fluorescent …
RPM Wong, H Karunajeewa, I Mueller… - Antimicrobial Agents …, 2011 - Am Soc Microbiol
Surveillance for Plasmodium falciparum drug resistance mutations is becoming an
established tool for assessing antimalarial treatment effectiveness. We used an extended …
established tool for assessing antimalarial treatment effectiveness. We used an extended …
Differential genetic hitchhiking around mutant pfcrt alleles in the Indian Plasmodium falciparum population
Objectives To study the origin and spread of the chloroquine-resistant Plasmodium
falciparum population in the Indian subcontinent. Methods Fourteen microsatellites …
falciparum population in the Indian subcontinent. Methods Fourteen microsatellites …