Poxvirus immune evasion
B Hernaez, A Alcamí - Annual Review of Immunology, 2024 - annualreviews.org
Poxviruses have evolved a wide array of mechanisms to evade the immune response, and
we provide an overview of the different immunomodulatory strategies. Poxviruses prevent …
we provide an overview of the different immunomodulatory strategies. Poxviruses prevent …
The emerging roles of silver nanoparticles to target viral life cycle and detect viral pathogens
Along the line of recent vaccine advancements, new antiviral therapeutics are compelling to
combat viral infection‐related public health crises. Several properties of silver nanoparticles …
combat viral infection‐related public health crises. Several properties of silver nanoparticles …
Ancient gene capture and recent gene loss shape the evolution of orthopoxvirus-host interaction genes
The survival of viruses depends on their ability to resist host defenses and, of all animal virus
families, the poxviruses have the most antidefense genes. Orthopoxviruses (ORPV), a genus …
families, the poxviruses have the most antidefense genes. Orthopoxviruses (ORPV), a genus …
Rational design of a 'two-in-one'immunogen DAM drives potent immune response against mpox virus
H Wang, P Yin, T Zheng, L Qin, S Li, P Han, X Qu… - Nature …, 2024 - nature.com
The global outbreak of the mpox virus (MPXV) in 2022 highlights the urgent need for safer
and more accessible new-generation vaccines. Here, we used a structure-guided multi …
and more accessible new-generation vaccines. Here, we used a structure-guided multi …
Extended sequencing of vaccine and wild‐type capripoxvirus isolates provides insights into genes modulating virulence and host range
The genus Capripoxvirus in the subfamily Chordopoxvirinae, family Poxviridae, comprises
sheeppox virus (SPPV), goatpox virus (GTPV) and lumpy skin disease virus (LSDV), which …
sheeppox virus (SPPV), goatpox virus (GTPV) and lumpy skin disease virus (LSDV), which …
Poxviruses evade cytosolic sensing through disruption of an mTORC1-mTORC2 regulatory circuit
Viruses employ elaborate strategies to coopt the cellular processes they require to replicate
while simultaneously thwarting host antiviral responses. In many instances, how this is …
while simultaneously thwarting host antiviral responses. In many instances, how this is …
Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway
Myxoma virus (MYXV) causes localized cutaneous fibromas in its natural hosts, tapeti and
brush rabbits; however, in the European rabbit, MYXV causes the lethal disease …
brush rabbits; however, in the European rabbit, MYXV causes the lethal disease …
Vaccinia virus: from crude smallpox vaccines to elaborate viral vector vaccine design
O Kaynarcalidan, S Moreno Mascaraque, I Drexler - Biomedicines, 2021 - mdpi.com
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination
campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV …
campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV …
Quantitative temporal proteomic analysis of vaccinia virus infection reveals regulation of histone deacetylases by an interferon antagonist
Vaccinia virus (VACV) has numerous immune evasion strategies, including multiple
mechanisms of inhibition of interferon regulatory factor 3 (IRF-3), nuclear factor κB (NF-κB) …
mechanisms of inhibition of interferon regulatory factor 3 (IRF-3), nuclear factor κB (NF-κB) …
YTHDF2 is downregulated in response to host shutoff induced by DNA virus infection and regulates interferon-stimulated gene expression
CR Hesser, D Walsh - Journal of virology, 2023 - Am Soc Microbiol
Recent studies have begun to reveal the complex and multifunctional roles of N 6-
methyladenosine (m6A) modifications and their associated writer, reader, and eraser …
methyladenosine (m6A) modifications and their associated writer, reader, and eraser …