Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

During space travel astronauts are exposed to a variety of radiations, including galactic
cosmic rays composed of high-energy protons and high-energy charged (HZE) nuclei, and …

The disability, mortality and costs due to ionizing radiation (IR)-induced osteoporotic bone
fractures are substantial and no effective therapy exists. Ionizing radiation increases cellular …

The goal of radiation therapy is to provide the highest probability of tumor control while
minimizing normal tissue toxicity. Recently, it has been discovered that ultra-high dose rates …

High charge (Z) and energy (E)(HZE) nuclei are the main contributors to the uncertainty of
radiation risk in space. They ionize a large number of molecules when they interact with …

Relativistic heavy ions of high charge (Z) and energy (E)(HZE) in galactic cosmic rays (GCR)
are important contributors to space radiation risk because they cannot be shielded …

The focus of our laboratory's investigation is to study the direct-type DNA damage
mechanisms resulting from γ-ray and ion-beam radiation-induced free radical processes in …

FLASH radiotherapy appears to kill off tumor cells while sparing healthy tissues, by
irradiation at ultra high dose rate (> 40 Gy s− 1). The present study aims to clarify the …

We investigated the roles of gap junction communication and oxidative stress in modulating
potentially lethal damage repair in human fibroblast cultures exposed to doses of α particles …

Significance: During deep space travel, astronauts are often exposed to high atomic number
(Z) and high-energy (E)(high charge and high energy [HZE]) particles. On interaction with …