Breast cancer, as one of the most common invasive malignancies and the leading cause of
cancer‐related deaths in women globally, poses a significant challenge in the world health …

Amino-1, 3-dimethyluracil (1) has two electron donating centres (NH 2 and C-5) and its
chemical reactivity was investigated towards a variety of electrophilic reagents hoping to …

In this study, we designed and synthesized several novel fused [1, 2, 3] triazolo [4′, 5′: 3,
4] pyrrolo [2, 1-b] quinazolinone derivatives using a single [3+ 2] reaction cycloaddition …

Synthetic chemists have organized easy and effective ways for perfect synthesis in response
to the requirement for scaffolds that are crucial for medical applications. A general strategy …

ABSTRACT A general strategy was developed for the synthesis of new fully decorated 1, 2,
3‐triazoles (4a–4m and 5a–5g) containing quinazolines from 1‐(4‐nitrophenyl)‐2 …

A series of 20 novel gefitinib derivatives incorporating the 1, 2, 3-triazole moiety were
designed and synthesized. The synthesized compounds were evaluated for their potential …

Abstract The reaction of 4‐(chloroacetamido) pyrimidine (1) with ammonium thiocyanate
gave 2‐(pyrimidin‐4‐ylimino) thiazolidin‐4‐one (2), which, when condensed with four …

An efficient one-pot approach was proposed for the synthesis of novel sulfonyl-1 H-1, 2, 3-
triazolo-1 H-imidazole-2-sulfonamides. The newly synthesized derivatives were screened …

This study reports the synthesis and characterization of novel 4, 5, 6, 7-tetrahydrobenzo [b]
thiophene-3-carbonitrile (THBTC) derivatives. Compounds 3–12 were synthesized via N …

The thiazole ring closure of thiosemicarbazones with α-bromo-4-substituted acetophenones
was carried out to generate aminothiazole analogues (A1–A16). Experimental methods …