It is generally acknowledged that reactive oxygen species (ROS) play crucial roles in a
variety of natural processes in cells. If increased to levels which cannot be neutralized by the …

Seattle, Washington 98195 Changeux—are better established for NO/O2. This hemoglobin-
based paradigm for protein regulation (JSS, Two signaling systems, based on the principle …

Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) that has quickly and …

Interferon (IFN)-γ, is not only a marker of TH1 CD4, CD8 and natural killer (NK) cells, it is
also a critical antiviral mediator which is central to the elimination of viruses from the CNS. In …

The transfer of a nitric oxide group to cysteine sulfhydryls on proteins, known as S-
nitrosylation, is increasingly becoming recognized as a ubiquitous regulatory reaction …

The immune response to Mycobacterium tuberculosis (Mtb) includes expression of nitric
oxide (NO) synthase (NOS) 2, whose products can kill Mtb in vitro with a molar potency …

The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the greatest worldwide …

S-Nitrosoglutathione (GSNO), a naturally occurring constituent of airway lining fluid,
enhances ciliary motility, relaxes airway smooth muscle, inhibits airway epithelial amiloride …

Nitric oxide (NO) is an important biologically active molecule that plays a key part in host
defence against bacteria, protozoa, and tumour cells. NO has antiviral effects against …

Reactive nitrogen species (RNS) including nitric oxide (NO) are important components of
stress signaling. However, RNS-mediated signaling in the apoplast remains largely …