In order to ensure normal body function, the human body is dependent on a tight control of
its blood glucose levels. This is accomplished by a highly sophisticated network of various …

The enteroendocrine system orchestrates how the body responds to the ingestion of foods,
employing a diversity of hormones to fine-tune a wide range of physiological responses both …

G-protein coupled receptors (GPCRs) regulate hormone secretion from islets of Langerhans,
and recently developed therapies for type-2 diabetes target islet GLP-1 receptors. However …

Decretins, hormones induced by fasting that suppress insulin production and secretion,
have been postulated from classical human metabolic studies. From genetic screens, we …

Abstract BACKGROUND Neuromedin U (NmU) belongs to the neuromedin family,
comprising a series of neuropeptides involved in the gut–brain axis and including …

More than 35 years have passed since the identification of neuromedin U (NMU). Dozens of
publications have been devoted to its physiological role in the organism, which have …

Neuromedin U (NMU) has been paired with the G‐protein‐coupled receptors (GPRs) NMU1
(formely designated as the orphan GPR66 or FM‐3) and NMU2 (FM‐4 or hTGR‐1) …

Neuromedin U (NMU) is a highly conserved peptide reported to modulate energy
homeostasis. Pharmacological studies have shown that centrally administered NMU inhibits …

Neuropeptides are small protein used by neurons in signal communications. Neuromedin U
was the first neuropeptide discovered from the porcine spinal and showed its potent …

Neuromedin U (NmU), a multifunctional neuropeptide, belongs to a family of neuropeptides,
the neuromedins. It is ubiquitously distributed with highest levels found in the …