More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …

Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder.
Typically, it is characterized by hirsutism, hyperandrogenism, ovulatory dysfunction …

Background Gonadal steroid hormones have been suggested as the underlying mechanism
responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have …

In brief Sex differences in the gut microbiome may impact multiple aspects of human health
and disease. In this study, we review the evidence for microbial sex differences in puberty …

The etiology of polycystic ovary syndrome (PCOS) remains unclear, although studies
indicate that both genetic and environmental factors contribute to the syndrome. In 2012 …

The highly active estrogen metabolism and receptor protein expression are to blame for the
elevated breast cancer (BC) rate in post-menopausal women. Letrozole is a powerful …

Context The key gut microbial biomarkers for polycystic ovarian syndrome (PCOS) and how
dysbiosis causes insulin resistance and PCOS remain unclear. Objective To assess the …

Accumulating evidence suggested that both gut microbiome and sex play a critical role in
the efficacy of immune checkpoint blockade therapy. Considering the reciprocal relationship …

Polycystic ovary syndrome (PCOS), a common reproductive disorder in women, is
characterized by hyperandrogenemia, chronic anovulation, cystic ovarian follicles, and …

Polycystic ovarian syndrome (PCOS), characterized by chronic anovulation and
hyperandrogenaemia, is a complex endocrine and metabolic disorder commonly seen in …