Mechanisms of RNA export and nuclear retention

M Khan, S Hou, M Chen, H Lei - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
With the identification of huge amount of noncoding RNAs in recent years, the concept of
RNA localization has extended from traditional mRNA export to RNA export of mRNA and …

Alternative splicing of viral transcripts: the dark side of HBV

D Kremsdorf, B Lekbaby, P Bablon, J Sotty, J Augustin… - Gut, 2021 - gut.bmj.com
Regulation of alternative splicing is one of the most efficient mechanisms to enlarge the
proteomic diversity in eukaryotic organisms. Many viruses hijack the splicing machinery …

HBsAg mRNA degradation induced by a dihydroquinolizinone compound depends on the HBV posttranscriptional regulatory element

T Zhou, T Block, F Liu, AS Kondratowicz, L Sun… - Antiviral Research, 2018 - Elsevier
In pursuit of novel therapeutics targeting the hepatitis B virus (HBV) infection, we evaluated a
dihydroquinolizinone compound (DHQ-1) that in the nanomolar range reduced the …

Involvement of PUF60 in transcriptional and post-transcriptional regulation of hepatitis B virus pregenomic RNA expression

S Sun, K Nakashima, M Ito, Y Li, T Chida… - Scientific Reports, 2017 - nature.com
Here we identified PUF60, a splicing factor and a U2 small nuclear ribonucleoprotein
auxiliary factor, as a versatile regulator of transcriptional and post-transcriptional steps in …

Hepatitis B virus nuclear export elements: RNA stem-loop α and β, key parts of the HBV post-transcriptional regulatory element

CS Lim, CM Brown - RNA biology, 2016 - Taylor & Francis
Many viruses contain RNA elements that modulate splicing and/or promote nuclear export of
their RNAs. The RNAs of the major human pathogen, hepatitis B virus (HBV) contain a large …

The impact of hepatitis B virus (HBV) splicing on HBV replication and disease progression

LC McCoullough, M Littlejohn… - Exploration of Digestive …, 2024 - explorationpub.com
Chronic hepatitis B (CHB) disease caused by persistent infection with hepatitis B virus (HBV)
is a global health problem affecting almost 300 million people worldwide, resulting in up to 1 …

[HTML][HTML] Nuclear export of viral RNAs in metazoan

J Kubina, JP Gales, A Geldreich, C Bouton, M Keller… - Virologie, 2020 - jle.com
L'export nucléaire des ARNm est un processus complexe qui nécessite la participation
orchestrée de nombreuses protéines, dont le recrutement débute dès les premières étapes …

[PDF][PDF] Export nucléaire des ARN viraux chez les métazoaires.

J Kubina, JP Gales, A Geldreich, C Bouton, M Keller… - Virologie, 2020 - researchgate.net
L'export nucléaire des ARNm est un processus complexe qui nécessite la participation
orchestrée de nombreuses protéines, dont le recrutement débute dès les premières étapes …