[HTML][HTML] Physiological and pathological functions of circular RNAs in the nervous system

M Zhou, S Li, C Huang - Neural Regeneration Research, 2024 - journals.lww.com
Circular RNAs (circRNAs) are a class of covalently closed single-stranded RNAs that are
expressed during the development of specific cells and tissues. CircRNAs play crucial roles …

Roles of aging, circular RNAs, and RNA editing in the pathogenesis of amyotrophic lateral sclerosis: potential biomarkers and therapeutic targets

T Hosaka, H Tsuji, S Kwak - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is an incurable motor neuron disease caused by upper
and lower motor neuron death. Despite advances in our understanding of ALS …

A novel protein encoded by circKANSL1L regulates skeletal myogenesis via the Akt-FoxO3 signaling axis

Z Lin, F Xie, X He, J Wang, J Luo, T Chen… - International Journal of …, 2024 - Elsevier
Skeletal muscle is one the largest organs of the body and is involved in animal production
and human health. Circular RNAs (circRNAs) have been implicated in skeletal myogenesis …

Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis: a narrative review

PH King - Neural Regeneration Research, 2024 - journals.lww.com
Amyotrophic lateral sclerosis is a fatal multisystemic neurodegenerative disease with motor
neurons being a primary target. Although progressive weakness is a hallmark feature of …

Exploring the impact of circular RNA on ALS progression: A systematic review

S Panchalingam, G Kasivelu - Brain Research, 2024 - Elsevier
Amyotrophic lateral sclerosis is a neurodegenerative disease that damages motor neurons
and causes gradual muscular weakening and paralysis. Although studies have linked a …

Aberrantly Expressed Hsa_circ_0060762 and CSE1L as Potential Peripheral Blood Biomarkers for ALS

M Ravnik Glavač, M Mezzavilla, A Dolinar, B Koritnik… - Biomedicines, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive adult-onset neurodegenerative
disease that is often diagnosed with a delay due to initial non-specific symptoms. Therefore …

[HTML][HTML] Noches et al Epigenetics in ALS 1 Epigenetics in the formation of pathological aggregates in amyotrophic lateral sclerosis

V Noches, D Campos-Melo… - Frontiers in Molecular …, 2024 - frontiersin.org
The progressive degeneration of motor neurons in amyotrophic lateral sclerosis (ALS) is
accompanied by the formation of a broad array of cytoplasmic and nuclear neuronal …

RNA editing regulates glutamatergic synapses in the frontal cortex of a molecular subtype of Amyotrophic Lateral Sclerosis

K Karagianni, D Dafou, K Xanthopoulos, T Sklaviadis… - Molecular …, 2024 - Springer
Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a highly heterogenous
neurodegenerative disorder that primarily affects upper and lower motor neurons, affecting …

环状RNAs 在神经系统中的生理和病理功能

M Zhou, S Li, C Huang - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
环状RNAs 是一类共价闭合单链RNA 分子, 具有细胞/组织/发育特异性表达等特征. 环状RNAs
通过吸附microRNAs, 调节基因转录, 控制某些RNA 结合蛋白的活性, 以及产生功能肽等机制在 …

骨骼肌作为肌萎缩侧索硬化症疾病进展的分子和细胞生物标志物: 叙述性综述

PH King - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Amyotrophic lateral sclerosis is a fatal multisystemic neurodegenerative disease with motor
neurons being a primary target. Although progressive weakness is a hallmark feature of …