Challenges in developing cell culture media using machine learning

T Hashizume, BW Ying - Biotechnology Advances, 2024 - Elsevier
Microbial and mammalian cells are widely used in the food, pharmaceutical, and medical
industries. Developing or optimizing culture media is essential to improve cell culture …

Challenges and opportunities in bioprocessing of gellan gum: A review

N Sahu, B Mahanty, D Haldar - International Journal of Biological …, 2024 - Elsevier
Gellan gum (GG)—the microbial exopolysaccharide is increasingly being adopted into drug
development, tissue engineering, and food and pharmaceutical products. In spite of the …

Computational intelligence for empirical modeling and optimization of methylene blue adsorption phenomena using available local zeolites and clay of Morocco

R Tariq, M Abatal, A Bassam - Journal of Cleaner Production, 2022 - Elsevier
The present study investigated the performance of natural Moroccan zeolites and clay in the
removal of methylene blue (MB) from aqueous solutions. The deposits of the samples are …

COD and ammonia removal from landfill leachate by UV/PMS/Fe2+ process: ANN/RSM modeling and optimization

SY Masouleh, M Mozaffarian, B Dabir… - Process Safety and …, 2022 - Elsevier
Landfill leachate is a highly contaminated liquid generated in municipal solid waste landfills.
The application of sulfate radical-based advanced oxidation processes (SR-AOP) in landfill …

Recent advances in Emulsan production, purification, and application: Exploring bioemulsifiers unique potentials

AP D'Almeida, TL de Albuquerque… - International Journal of …, 2024 - Elsevier
Bioemulsifiers are compounds produced by microorganisms that reduce the interfacial
forces between hydrophobic substances and water. Due to their potential in the …

A review of algorithmic approaches for cell culture media optimization

T Zhou, R Reji, RS Kairon, KH Chiam - Frontiers in Bioengineering …, 2023 - frontiersin.org
Cell culture media composition and culture conditions play a crucial role in product yield,
quality and cost of production. Culture media optimization is the technique of improving …

[HTML][HTML] Dynamic evaluation of water resources carrying capacity of the Dianchi Lake Basin in 2005–2015, based on DSPERM framework model and simulated …

J Wang, X Mu, S Chen, W Liu, Z Wang, Z Dong - Regional Sustainability, 2021 - Elsevier
With the intensified impact of human activities, most lakes have been severely disturbed and
the lake ecosystem has been seriously damaged, which exerted a great impact on the living …

Sugarcane bagasse pretreated by different technologies used as support and carbon source in solid-state fermentation by Aureobasidium pullulans LB83 to produce …

RAM da Costa, D Rubio-Ribeaux, BC Carneiro… - Biomass conversion and …, 2024 - Springer
Bioemulsifier production by Aureobasidium pullulans LB83 from pretreated sugarcane
bagasse was evaluated in solid-state fermentation. Alkaline (0.2 mol. L− 1 NaOH; 12 min) …

Synergistic effects of ternary mixture formulation and process parameters optimization in a sequential approach for enhanced L-asparaginase production using agro …

D Sharma, A Mishra - Environmental Science and Pollution Research, 2024 - Springer
A novel ternary mixture of inexpensive and nutrient-rich agro-substrates comprising
groundnut de-oiled cake, corn gluten meal, and soybean meal has been explored to …

Comparing a polynomial DOE model and an ANN model for enhanced geranyl cinnamate biosynthesis with Novozym® 435 lipase

JFC do Nascimento, BD dos Reis… - Biocatalysis and …, 2024 - Elsevier
Abstract Central Composite Rotatable Design (CCRD), a type of factorial design of
experiment is among the most traditional methods used for optimizing bioprocesses, but, in …