CFD for evaluation and treatment planning of aneurysms: review of proposed clinical uses and their challenges

B Chung, JR Cebral - Annals of biomedical engineering, 2015 - Springer
Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …

Data-driven cardiovascular flow modelling: examples and opportunities

A Arzani, STM Dawson - Journal of the Royal Society …, 2021 - royalsocietypublishing.org
High-fidelity blood flow modelling is crucial for enhancing our understanding of
cardiovascular disease. Despite significant advances in computational and experimental …

Physical factors effecting cerebral aneurysm pathophysiology

C Sadasivan, DJ Fiorella, HH Woo… - Annals of biomedical …, 2013 - Springer
Many factors that are either blood-, wall-, or hemodynamics-borne have been associated
with the initiation, growth, and rupture of intracranial aneurysms. The distribution of cerebral …

An introduction with medical applications to functional data analysis

H Sørensen, J Goldsmith, LM Sangalli - Statistics in medicine, 2013 - Wiley Online Library
Functional data are data that can be represented by suitable functions, such as curves
(potentially multi‐dimensional) or surfaces. This paper gives an introduction to some basic …

Wall shear stress at the initiation site of cerebral aneurysms

AJ Geers, HG Morales, I Larrabide, C Butakoff… - … and modeling in …, 2017 - Springer
Hemodynamics are believed to play an important role in the initiation of cerebral aneurysms.
In particular, studies have focused on wall shear stress (WSS), which is a key regulator of …

Factors affecting formation and rupture of intracranial saccular aneurysms

S Bacigaluppi, M Piccinelli, L Antiga, A Veneziani… - Neurosurgical …, 2014 - Springer
Unruptured intracranial aneurysms represent a decisional challenge. Treatment risks have
to be balanced against an unknown probability of rupture. A better understanding of the …

Automatic neck plane detection and 3D geometric characterization of aneurysmal sacs

M Piccinelli, DA Steinman, Y Hoi, F Tong… - Annals of biomedical …, 2012 - Springer
Geometric indices defined on intracranial aneurysms have been widely used in rupture risk
assessment and surgical planning. However, most indices employed in clinical settings are …

Spatial regression models over two-dimensional manifolds

B Ettinger, S Perotto, LM Sangalli - Biometrika, 2016 - academic.oup.com
We propose a regression model for data spatially distributed over general two-dimensional
Riemannian manifolds. This is a generalized additive model with a roughness penalty term …

Validation of an open source framework for the simulation of blood flow in rigid and deformable vessels

T Passerini, A Quaini, U Villa… - … journal for numerical …, 2013 - Wiley Online Library
We discuss in this paper the validation of an open source framework for the solution of
problems arising in hemodynamics. The proposed framework is assessed through …

The LifeV library: engineering mathematics beyond the proof of concept

L Bertagna, S Deparis, L Formaggia, D Forti… - arXiv preprint arXiv …, 2017 - arxiv.org
LifeV is a library for the finite element (FE) solution of partial differential equations in one,
two, and three dimensions. It is written in C++ and designed to run on diverse parallel …