Skeletal muscle dysfunctions in pulmonary arterial hypertension: Effects of aerobic exercise training

FR Drummond, LB Leite, DC de Miranda… - Frontiers in …, 2023 - frontiersin.org
Pulmonary arterial hypertension is associated with skeletal muscle myopathy and atrophy
and impaired exercise tolerance. Aerobic exercise training has been recommended as a …

Effects of exercise rehabilitation training on patients with pulmonary hypertension

X Zhang, D Xu - Pulmonary Circulation, 2020 - journals.sagepub.com
Pulmonary hypertension (PH) comprises a group of pathophysiological syndromes
characterized by elevated pulmonary artery pressure and pulmonary vascular resistance …

Effects of exercise training on circulating biomarkers of endothelial function in pulmonary arterial hypertension

DA Rodríguez-Chiaradía, K Khilzi, I Blanco… - Biomedicines, 2023 - mdpi.com
Introduction: In stable patients with pulmonary arterial hypertension (PAH), pulmonary
rehabilitation (PR) is an effective, safe and cost-effective non-pharmacological treatment …

Effects of voluntary running on the skeletal muscle of rats with pulmonary artery hypertension

FR Drummond, LL Soares, TF Leal, LB Leite… - Frontiers in …, 2023 - frontiersin.org
The effects of voluntary running on the skeletal muscle of rats with pulmonary arterial
hypertension (PAH) were tested in the present study. PAH was induced in rats by a single …

Resistance exercise training benefits pulmonary, cardiac, and muscular structure and function in rats with stable pulmonary artery hypertension

LL Soares, LB Leite, LOG Ervilha, BRA Pelozin… - Life Sciences, 2023 - Elsevier
Aim We tested the effects of low-to moderate-intensity resistance exercise training (RT) on
the structure and function of pulmonary, right ventricle (RV), and skeletal muscle tissues in …

The effect of blood flow-restricted low resistance training on microvascular circulation of myocardium in spontaneously hypertensive rats

Z Tan, Y Zhao, Y Zheng, Y Pan - Frontiers in Physiology, 2022 - frontiersin.org
Objective: The purpose of this study was to explore the effect of blood flow-restricted low
resistance training on microvascular rarefaction in the myocardium of spontaneously …

Resistance exercise training mitigates left ventricular dysfunctions in pulmonary artery hypertension model

LL Soares, LB Leite, LOG Ervilha, BAF Silva… - Arquivos Brasileiros …, 2022 - SciELO Brasil
Background: The right ventricular hypertrophy and dilation observed in pulmonary artery
hypertension (PAH) damages the left ventricle (LV) dynamics by flattening the …

Continuous aerobic exercise prevents detrimental remodeling and right heart myocyte contraction and calcium cycling dysfunction in pulmonary artery hypertension

F de Jesus Silva, FR Drummond… - Journal of …, 2021 - journals.lww.com
Pulmonary artery hypertension (PAH) imposes right heart and lung detrimental remodeling
which impairs cardiac contractility, physical effort tolerance, and survival. The effects of an …

Combined exercise hinders the progression of pulmonary and right heart harmful remodeling in monocrotaline-induced pulmonary arterial hypertension

LB Leite, LL Soares, AMO Portes… - Journal of Applied …, 2025 - journals.physiology.org
The aim of this study was to test whether combined physical exercise training of moderate
intensity executed during the development of monocrotaline (MCT)-induced pulmonary …

Autonomic Dysregulation in Pulmonary Hypertension: Role of Physical Exercise

L Lopes Soares, AMO Portes, SFF Costa, LB Leite… - …, 2024 - ahajournals.org
Pulmonary hypertension (PH) is a rare and severe condition characterized by increased
pressure in the pulmonary circulation, often resulting in right ventricular failure and death …