Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

Following the discovery of leptin in 1994, the scientific and clinical communities have held
great hope that manipulation of the leptin axis may lead to the successful treatment of …

Obesity markedly increases the odds of developing depression. Depressed mood not only
impairs motivation, quality of life and overall functioning but also increases the risks of …

Purpose: To review recent advances in the pathophysiology and potential clinical
applications of leptin, an adipose tissue-derived hormone. Data Sources: A MEDLINE …

Leptin, a hormone secreted from adipose tissue, was originally discovered to regulate body
weight. The localization of the leptin receptor in limbic structures suggests a potential role for …

Body weight gain frequently occurs during drug treatment of psychiatric disorders and is
often accompanied by increased appetite or food craving. While occurrence and time course …

The adipose-derived hormone leptin is well known for its function in the control of energy
homeostasis. Recent studies suggest a novel role for this adipokine in the regulation of …

Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …

Obesity and related metabolic conditions are of epidemic proportions in most of the world,
affecting both adults and children. The accumulation of lipids in the body in the form of white …

Currently, the diagnosis of major depressive disorder (MDD) mainly relies on clinical
examination and subjective evaluation of depressive symptoms. There is no non-invasive …