Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …

Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …

Coupling materials chemistry systems to biological processes is a promising way to
rationally modulate lysosomal functions. A proton‐driven dynamic assembly of a DNA …

Asparagine endopeptidase (AEP), also called legumain, is currently the only known cysteine
protease that specifically cleaves peptide bonds in asparaginyl residue in the mammalian …

DNA nanotechnology is a rapidly growing field that provides exciting tools for biomedical
applications. Targeting lysosomal functions with nanomaterials, such as DNA …

Rationale: The compensatory activation of the renin-angiotensin system (RAS) after
myocardial infarction (MI) plays a crucial role in the pathogenesis of heart failure. Most …

Enzyme-instructed self-assembly (EISA) and hydrogelation is a versatile approach for
generating soft materials. Most of the substrates for alkaline phosphatase catalysed EISA …

Receptors of carbohydrate mannose-6-phosphate (M6P) are overexpressed in specific
cancer cells (such as breast cancer) and are also involved in the trafficking of mannose-6 …

Inducing high levels of reactive oxygen species (ROS) inside tumor cells is a cancer therapy
method termed chemodynamic therapy (CDT). Relying on delivery of Fenton reaction …

Enhancing the accumulation and retention of small-molecule probes in tumors is an
important way to achieve accurate cancer diagnosis and therapy. Enzyme-stimulated …