The environment, diet, microbiota and body's metabolism shape complex biological
processes in health and disease. However, our understanding of the molecular pathways …

The aryl hydrocarbon receptor (AHR) is widely expressed in immune and non-immune cells
of the gut and its activation has been correlated to the outcome of inflammatory bowel …

The aryl hydrocarbon receptor (AhR) was first identified as the intracellular protein that
bound and mediated the toxic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) …

Despite being banned from production for decades, polychlorinated biphenyls (PCBs)
continue to pose a significant risk to human health. This is due to not only the continued …

The aryl hydrocarbon receptor (or AhR) is a cytoplasmic receptor of pollutants. It translocates
into the nucleus upon binding to its ligands, and forms a heterodimer with ARNT (AhR …

Sporadic late-onset Alzheimer's disease (AD) is the most frequent cause of dementia
associated with aging. Due to the progressive aging of the population, AD is becoming a …

The aryl hydrocarbon receptor (AHR) was for many years of interest only to pharmacologists
and toxicologists. However, this protein has fundamental roles in biology that are being …

Background & Aims The enteric nervous system (ENS) regulates gastrointestinal function via
different subtypes of neurons, organized into fine-tuned neural circuits. It is not clear how cell …

Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances
(PFASs), brominated flame retardants (BFRs), organochlorine pesticides and …

Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid
displaying significant potential in various biological activities. The chemical structure of …