Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
degeneration of motor neurons in the brain and spinal cord. The causes of ALS are not fully …

Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative
disease characterized by the progressive loss of upper and lower motor neurons. ALS …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor
neurons. Recently, genome-wide association studies identified KIF5A as a new ALS …

KIF5A is a kinesin superfamily motor protein that transports various cargos in neurons.
Mutations in Kif5a cause familial amyotrophic lateral sclerosis (ALS). These ALS mutations …

Despite continuing progress in kinesin enzyme mechanochemistry and emerging
understanding of the cargo recognition machinery, it is not known how these functions are …

The localization of RNAs in cells is critical for many cellular processes. Whereas motor‐
driven transport of ribonucleoprotein (RNP) condensates plays a prominent role in RNA …

Accurate chromosome segregation during cell division relies on coordinated actions of
microtubule (MT)-based motor proteins in the mitotic spindle. Kinesin-14 motors play vital …

Kinesin-1, composed of kinesin heavy chain and kinesin light chain, is a founding member
of kinesin superfamily and transports various neuronal cargos. Kinesin-1 is one of the most …

RNA binding proteins (RBPs) act as critical facilitators of spatially regulated gene
expression. Muscleblind-like (MBNL) proteins, implicated in myotonic dystrophy and cancer …

Amyotrophic lateral sclerosis (ALS) is regarded as a fatal neurodegenerative disease that is
featured by progressive damage of the upper and lower motor neurons. To date, over 45 …