Chromatin disruption and modification
AP Wolffe, JJ Hayes - Nucleic acids research, 1999 - academic.oup.com
Chromatin disruption and modification are associated with transcriptional regulation by
diverse coactivators and corepressors. Here we discuss the possible structural basis and …
diverse coactivators and corepressors. Here we discuss the possible structural basis and …
The physics of chromatin
H Schiessel - Journal of Physics: Condensed Matter, 2003 - iopscience.iop.org
Recent progress has been made in the understanding of the physical properties of
chromatin—the dense complex of DNA and histone proteins that occupies the nuclei of plant …
chromatin—the dense complex of DNA and histone proteins that occupies the nuclei of plant …
Crystal structure of the nucleosome core particle at 2.8 Å resolution
K Luger, AW Mäder, RK Richmond, DF Sargent… - Nature, 1997 - nature.com
The X-ray crystal structure of the nucleosome core particle of chromatin shows in atomic
detail how the histone protein octamer is assembled and how 146 base pairs of DNA are …
detail how the histone protein octamer is assembled and how 146 base pairs of DNA are …
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 Å resolution
Solvent binding in the nucleosome core particle containing a 147 base pair, defined-
sequence DNA is characterized from the X-ray crystal structure at 1.9 Å resolution. A single …
sequence DNA is characterized from the X-ray crystal structure at 1.9 Å resolution. A single …
The structure of DNA in the nucleosome core
TJ Richmond, CA Davey - Nature, 2003 - nature.com
Abstract The 1.9-Å-resolution crystal structure of the nucleosome core particle containing
147 DNA base pairs reveals the conformation of nucleosomal DNA with unprecedented …
147 DNA base pairs reveals the conformation of nucleosomal DNA with unprecedented …
Preparation of nucleosome core particle from recombinant histones
K Luger, TJ Rechsteiner, TJ Richmond - Methods in enzymology, 1999 - Elsevier
Publisher Summary This chapter describes the preparation method of nucleosome core
particles (NCPs) from recombinant histones. The ability to make defined NCPs, or arrays of …
particles (NCPs) from recombinant histones. The ability to make defined NCPs, or arrays of …
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
Genetic imprinting, found in flowering plants and placental mammals, uses DNA methylation
to yield gene expression that is dependent on the parent of origin. DNA methyltransferase …
to yield gene expression that is dependent on the parent of origin. DNA methyltransferase …
ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference
ATP-dependent chromatin remodellers regulate access to genetic information by controlling
nucleosome positions in vivo. However, the mechanism by which remodellers discriminate …
nucleosome positions in vivo. However, the mechanism by which remodellers discriminate …
Nucleosome mobilization catalysed by the yeast SWI/SNF complex
The generation of a local chromatin topology conducive to transcription is a key step in gene
regulation 1. The yeast SWI/SNF complex is the founding member of a family of ATP …
regulation 1. The yeast SWI/SNF complex is the founding member of a family of ATP …
ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF
Drosophila NURF is an ATP-dependent chromatin remodeling complex that contains ISWI, a
member of the SWI2/SNF2 family of ATPases. We demonstrate that NURF catalyzes the …
member of the SWI2/SNF2 family of ATPases. We demonstrate that NURF catalyzes the …