The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

Mapping brain asymmetry in health and disease through the ENIGMA consortium

XZ Kong, MC Postema, T Guadalupe… - Human brain …, 2022 - Wiley Online Library
Left–right asymmetry of the human brain is one of its cardinal features, and also a complex,
multivariate trait. Decades of research have suggested that brain asymmetry may be altered …

Atypical functional connectome hierarchy in autism

SJ Hong, R Vos de Wael, RAI Bethlehem… - Nature …, 2019 - nature.com
One paradox of autism is the co-occurrence of deficits in sensory and higher-order socio-
cognitive processing. Here, we examined whether these phenotypical patterns may relate to …

Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

MC Postema, D Van Rooij, E Anagnostou… - Nature …, 2019 - nature.com
Altered structural brain asymmetry in autism spectrum disorder (ASD) has been reported.
However, findings have been inconsistent, likely due to limited sample sizes. Here we …

Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism

B Park, SJ Hong, SL Valk, C Paquola… - Nature …, 2021 - nature.com
The pathophysiology of autism has been suggested to involve a combination of both
macroscale connectome miswiring and microcircuit anomalies. Here, we combine …

Resting state EEG power spectrum and functional connectivity in autism: a cross-sectional analysis

P Garcés, S Baumeister, L Mason, CH Chatham… - Molecular autism, 2022 - Springer
Background Understanding the development of the neuronal circuitry underlying autism
spectrum disorder (ASD) is critical to shed light into its etiology and for the development of …

Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging

O Benkarim, C Paquola, B Park, V Kebets, SJ Hong… - PLoS …, 2022 - journals.plos.org
Brain imaging research enjoys increasing adoption of supervised machine learning for
single-participant disease classification. Yet, the success of these algorithms likely depends …

Connectivity alterations in autism reflect functional idiosyncrasy

O Benkarim, C Paquola, B Park, SJ Hong… - Communications …, 2021 - nature.com
Autism spectrum disorder (ASD) is commonly understood as an alteration of brain networks,
yet case-control analyses against typically-developing controls (TD) have yielded …

[HTML][HTML] The functional brain organization of an individual allows prediction of measures of social abilities transdiagnostically in autism and attention-deficit …

EMR Lake, ES Finn, SM Noble, T Vanderwal, X Shen… - Biological …, 2019 - Elsevier
Background Autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD)
are associated with complex changes as revealed by functional magnetic resonance …

[HTML][HTML] Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex

R Babij, C Ferrer, A Donatelle, S Wacks, AM Buch… - Neuron, 2023 - cell.com
Dysfunction of gamma-aminobutyric acid (GABA) ergic circuits is strongly associated with
neurodevelopmental disorders. However, it is unclear how genetic predispositions impact …