Irisin as a multifunctional protein: implications for health and certain diseases

P Korta, E Pocheć, A Mazur-Biały - Medicina, 2019 - mdpi.com
Sedentary life style is considered to be an independent risk factor for many disorders,
including development of type 2 diabetes, obesity, immune dysfunction, asthma, and …

Body temperature regulation in diabetes

GP Kenny, RJ Sigal, R McGinn - Temperature, 2016 - Taylor & Francis
The effects of type 1 and type 2 diabetes on the body's physiological response to thermal
stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk …

Anti-obesity effects of metformin: a scoping review evaluating the feasibility of brown adipose tissue as a therapeutic target

K Ziqubu, SE Mazibuko-Mbeje, SXH Mthembu… - International Journal of …, 2023 - mdpi.com
Brown adipose tissue (BAT) is increasingly recognized as the major therapeutic target to
promote energy expenditure and ameliorate diverse metabolic complications. There is a …

Tea Plant (Camellia sinensis): A Current Update on Use in Diabetes, Obesity, and Cardiovascular Disease

JM Brimson, MI Prasanth, KK Kumaree… - Nutrients, 2022 - mdpi.com
The tea plant (C. sinensis) has traditionally been consumed worldwide as “tea” for its many
health benefits, with the potential for the prevention and therapy of various conditions …

Signaling pathways regulating thermogenesis

C Tabuchi, HS Sul - Frontiers in endocrinology, 2021 - frontiersin.org
Obesity, an excess accumulation of white adipose tissue (WAT), has become a global
epidemic and is associated with complex diseases, such as type 2 diabetes and …

Inter‐relationships of the chronobiotic, melatonin, with leptin and adiponectin: implications for obesity

K Szewczyk‐Golec, A Woźniak… - Journal of pineal …, 2015 - Wiley Online Library
Obesity and its medical complications represent a significant problem throughout the world.
In recent decades, mechanisms underlying the progression of obesity have been intensively …

Metrnl: a secreted protein with new emerging functions

S Zheng, Z Li, J Song, J Liu, C Miao - Acta pharmacologica sinica, 2016 - nature.com
Secreted proteins play critical roles in physiological and pathological processes and can be
used as biomarkers and therapies for aging and disease. Metrnl is a novel secreted protein …

Effects and mechanisms of tea on obesity

XY Xu, CN Zhao, BY Li, GY Tang, A Shang… - Critical Reviews in …, 2023 - Taylor & Francis
Obesity has become a global health concern. It increases the risk of several diseases, such
as type 2 diabetes mellitus, nonalcoholic fatty liver disease, and certain cancers, which …

Extracellular vesicle therapy for obesity-induced NAFLD: A comprehensive review of current evidence

J Zhang, B Ma, Z Wang, Y Chen, C Li… - Cell Communication and …, 2024 - Springer
Non-alcoholic fatty liver disease (NAFLD) as a chronic disease especially in Western
countries, is still a tough question in the clinical therapy. With the rising prevalence of …

The impact of the adipose organ plasticity on inflammation and cancer progression

LH Corrêa, GS Heyn, KG Magalhaes - Cells, 2019 - mdpi.com
Obesity is characterized by chronic and low-grade systemic inflammation, an increase of
adipose tissue, hypertrophy, and hyperplasia of adipocytes. Adipose tissues can be …