Recent advances in the monitoring, modelling and control of crystallization systems

ZK Nagy, G Fevotte, H Kramer, LL Simon - Chemical Engineering Research …, 2013 - Elsevier
Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …

Engineering crystal morphology

P Dandekar, ZB Kuvadia… - Annual Review of …, 2013 - annualreviews.org
Crystallization is an important separation and particle formation technique in the
manufacture of high-value-added products. During crystallization, many physicochemical …

Influence of particle size and shape properties on cake resistance and compressibility during pressure filtration

D Bourcier, JP Féraud, D Colson, K Mandrick… - Chemical Engineering …, 2016 - Elsevier
The aim of this paper was to study cake filterability and compressibility as a function of the
particle shape and particle size distribution (PSD). Different shapes and PSD of calcium …

Characterizing variability in lignocellulosic biomass: a review

J Yan, O Oyedeji, JH Leal, BS Donohoe… - ACS Sustainable …, 2020 - ACS Publications
Feedstock variability is a significant barrier to the scale-up and commercialization of
lignocellulosic biofuel technologies. Variability in feedstock characteristics and behavior …

In Situ Imaging Combined with Deep Learning for Crystallization Process Monitoring: Application to Cephalexin Production

H Salami, MA McDonald, AS Bommarius… - … Process Research & …, 2021 - ACS Publications
The online detection of a trace amount of an undesired solid phase within a crystal slurry
can enable feedback control to improve product purity, decrease batch rejection, and …

Image Analysis for In-line Measurement of Multidimensional Size, Shape, and Polymorphic Transformation of l-Glutamic Acid Using Deep Learning-Based Image …

Z Gao, Y Wu, Y Bao, J Gong, J Wang… - Crystal Growth & …, 2018 - ACS Publications
In situ tracking of the crystallization process through image segmentation has been
developed and has encountered many challenges including improvement of in situ image …

Habit modification in pharmaceutical crystallization: A review

S Pu, K Hadinoto - Chemical Engineering Research and Design, 2024 - Elsevier
Besides size and purity, habit represents a critical quality attribute of pharmaceutical
crystals, influencing efficiencies of downstream processing steps and final drug product's …

High accuracy online measurement of multidimensional particle size distributions during crystallization

S Schorsch, DR Ochsenbein, T Vetter, M Morari… - Chemical Engineering …, 2014 - Elsevier
A novel stereoscopic image acquisition setup and a procedure for measuring
multidimensional particle size distributions (nD PSDs) during crystallization based on image …

In-situ multi-phase flow imaging for particle dynamic tracking and characterization: Advances and applications

J Liu, W Kuang, J Liu, Z Gao, S Rohani… - Chemical Engineering …, 2022 - Elsevier
Real-time chemical process monitoring, analysis, and control have become increasingly
important to multi-phase flow process research and development and attracted overt …

Image-based in situ identification of face specific crystal growth rates from crystal populations

C Borchert, E Temmel, H Eisenschmidt… - Crystal Growth & …, 2014 - ACS Publications
Online microscopy has received much attention in the field of crystal shape control over
recent years, since commonly used measurement techniques cannot provide enough …