Biosynthesis, natural distribution, and biological activities of acyclic monoterpenes and their derivatives

ME Bergman, AE Franks, MA Phillips - Phytochemistry Reviews, 2023 - Springer
Monoterpenoids are C10 isoprenoid natural products with diverse functions as volatile and
non-volatile secondary metabolites. Their biosynthesis from acyclic diphosphate precursors …

A chromosome-level genome assembly reveals that tandem-duplicated CYP706V oxidase genes control oridonin biosynthesis in the shoot apex of Isodon rubescens

Y Sun, J Shao, H Liu, H Wang, G Wang, J Li, Y Mao… - Molecular Plant, 2023 - cell.com
The ent-kaurenoids (eg, oridonin and enmein) from the Isodon genus (Lamiaceae) are one
class of diterpenoids with rich structural diversity and intriguing pharmaceutical activity. In …

Emerging functions within the enzyme families of plant alkaloid biosynthesis

F Muro-Villanueva, RS Nett - Phytochemistry Reviews, 2023 - Springer
The alkaloids are a major class of nitrogen-containing plant specialized metabolites that
function as both toxic defense compounds and useful pharmaceuticals. Understanding the …

Identification and functional characterization of three iridoid synthases in Gardenia jasminoides

C Xu, P Ye, Q Wu, S Liang, W Wei, J Yang, W Chen… - Planta, 2022 - Springer
Main conclusion The discovery of three iridoid synthases (GjISY, GjISY2 and GjISY4) from
Gardenia jasminoides and their functional characterization increase the understanding of …

Functional evolution and diversification of CYP82D subfamily members have shaped flavonoid diversification in the genus Scutellaria

S Qiu, J Wang, T Pei, R Gao, C Xiang, J Chen… - Plant …, 2024 - cell.com
Flavonoids, the largest class of polyphenols, exhibit substantial structural and functional
diversity, yet their evolutionary diversification and specialized functions remain largely …

[HTML][HTML] The genomes of medicinal skullcaps reveal the polyphyletic origins of clerodane diterpene biosynthesis in the family Lamiaceae

H Li, S Wu, R Lin, Y Xiao, ALM Morotti, Y Wang… - Molecular Plant, 2023 - cell.com
The presence of anticancer clerodane diterpenoids is a chemotaxonomic marker for the
traditional Chinese medicinal plant Scutellaria barbata, although the molecular mechanisms …

Short-term salicylic acid application induces the expression of GPPS and NEPS1 in catnip

KA Allen, EN Gomes, A Lockhart, Q Wu, R Di… - … and Experimental Plant …, 2024 - Springer
The catnip plant, Nepeta cataria L., produces bioactive iridoid monoterpenes known as
nepetalactones. These monoterpenes follow a noncanonical biosynthetic route starting as …

In vivo characterization of key iridoid biosynthesis pathway genes in catnip (Nepeta cataria)

L Palmer, L Chuang, M Siegmund, M Kunert… - Planta, 2022 - Springer
Main conclusion Using virus-induced gene silencing, we demonstrated that the enzymes
GES, ISY, and MLPL are responsible for nepetalactone biosynthesis in Nepeta cataria …