Optogenetics for light control of biological systems

V Emiliani, E Entcheva, R Hedrich… - Nature Reviews …, 2022 - nature.com
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Towards translational optogenetics

A Bansal, S Shikha, Y Zhang - Nature Biomedical Engineering, 2023 - nature.com
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

T Patriarchi, JR Cho, K Merten, MW Howe, A Marley… - Science, 2018 - science.org
INTRODUCTION Neuromodulators, such as dopamine, norepinephrine, or serotonin, exert
powerful control over neural circuit dynamics that give rise to diverse neural function and …

Integration of optogenetics with complementary methodologies in systems neuroscience

CK Kim, A Adhikari, K Deisseroth - Nature Reviews Neuroscience, 2017 - nature.com
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

Plasmonic Ti3C2Tx MXene Enables Highly Efficient Photothermal Conversion for Healable and Transparent Wearable Device

X Fan, Y Ding, Y Liu, J Liang, Y Chen - ACS nano, 2019 - ACS Publications
Skin-mountable and transparent devices are highly desired for next-generation electronic
applications but are susceptible to unexpected ruptures or undesired scratches, which can …

Optical magnetic detection of single-neuron action potentials using quantum defects in diamond

JF Barry, MJ Turner, JM Schloss… - Proceedings of the …, 2016 - National Acad Sciences
Magnetic fields from neuronal action potentials (APs) pass largely unperturbed through
biological tissue, allowing magnetic measurements of AP dynamics to be performed …

A connectome of a learning and memory center in the adult Drosophila brain

S Takemura, Y Aso, T Hige, A Wong, Z Lu, CS Xu… - Elife, 2017 - elifesciences.org
Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …

Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo

A Canales, X Jia, UP Froriep, RA Koppes… - Nature …, 2015 - nature.com
Brain function depends on simultaneous electrical, chemical and mechanical signaling at
the cellular level. This multiplicity has confounded efforts to simultaneously measure or …

The origin of extracellular fields and currents—EEG, ECoG, LFP and spikes

G Buzsáki, CA Anastassiou, C Koch - Nature reviews neuroscience, 2012 - nature.com
Neuronal activity in the brain gives rise to transmembrane currents that can be measured in
the extracellular medium. Although the major contributor of the extracellular signal is the …